bone tumors Flashcards

(39 cards)

1
Q

Most malignant tumors are

A

painful

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2
Q

aggravating behaviors of malignant bone tumors

A

weight bearing

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3
Q

most benign tumors dont have

A

soft tissue masses

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4
Q

soft tissue tumors are often

A

mobile over the bone

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5
Q

osteoid osteoma is

A

benign but painful

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6
Q

radiographic features of bone tumors

4 of them

A

1) destruction of bone
2) periosteal reaction
3) soft tissue mass
4) matrix produced by tumor

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7
Q

Sunburst
onion-skinning and
codman’s triangle are
signs of

A

malignant periosteal reactions

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8
Q

Periosteal neocortex is a sign of

A

benign periosteal reaction

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9
Q

Sunburst or hair ends
and osteoid matrix
are typical features of

A

osteosarcoma

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10
Q

What is codman’s triangle

A

an angle of new bone that is formed along the cortex as the periosteum is lifted up by the tumor

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11
Q

Onion-skinning is a feature of

A

ewing’s sarcoma

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12
Q

A thing egg shell of new bone formed by periosteum is

A

neocortex -

and is benign aggressive

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13
Q

CLouds of bone that has been formed in medullary canal or soft tissue is

A

osteoid matrix - feature of osteosarcoma

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14
Q

punctate or popcorn calcification is a feature of

A

benign or malignant chondromas

- chondroid matrix

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15
Q

ground glass/ hazy matrix is

A

fibrous matrix

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16
Q

only benign tumor that will destroy bone is

A

giant cell tumor

17
Q
no soft tissue mass
normal ROM
no malignant radiographic features
but some matrix lesions
punctate calcifications
A

endochondroma - hyaline cartilage involving medullary bone

18
Q

where do endochondromas occur?

A

small bones of hands and feet

long tubular bones

19
Q

how large are endochondromas

A

< 3cm
white-grey
translucent
often multi-nodular

20
Q

how do endochondromas look like histologically

A

resemble hyaline cartilage

lack invasion

21
Q

A tumor composed of hyaline cartilage

A

chondrosarcoma

22
Q

sites of involvement of chondrosarcoma

A

pelvis
long tubular bones
ribs

23
Q

gross features of a chondrosarcoma

A

large
blue-grey
translucent
destructive

24
Q

how do you treat a chondrosarcoma

A

no chemorad

- SURGERY -

25
``` 13 yr old F pain and swelling Fever and night sweats Soft tissue mass onion skinning ```
ewing sarcoma
26
sites of involvement of ewing's sarcoma
- pelvis, ribs | long bones - diaphysis
27
Soft/friable tumor tan-grey hemorrhagic or necrotic
ewing's
28
Microscopic identification of ewing's sarcoma
Small round cell tumor | scant cytoplasm, lots of glycogen
29
malignant tumor very responsive to chemo
Ewing's
30
``` 22 yr old limp, effusion at knee swelling, tenderness, dec ROM eroded and neocortex egg shell neoplastic mononuclear cells ```
Giant cell tumor
31
hemorrhagic | Mononuclear cells interspersed with reactive osteoclast type GIANT cels
giant cell tumor
32
Tumor in which the metaphysis of long bones is involved | flat bones and spine on occasion
Giant cell tumor
33
16 yr old F progressive pain and swelling in left knee tenderness, effusion Osteoid - dense bone formation with soft tissue mass sunburst
osteosarcoma
34
tumor in which the neoplastic cells produce osteoid matrix
osteosarcoma
35
two tumors that involve METAPHYSIS
OSTEOSARCOMA | GIANT CELL tumors
36
large fleshy hard gray-white necrotic granular or densely sclerotic transgresses cortex with soft tissue mass
osteosarcoma
37
which tumors do not respond to radiotherapy
osteosarcomas | chondrosarcomas
38
``` 70 yr old cachectic clubbing lymphadenopathy lytic lesion erosion of cortex, no soft tissue mass or periosteal reaction ```
Metastatic disease with bone destruction
39
first treatment for bone mets
radiotherapy