Bones ch6 Flashcards

1
Q

functions of skeletal system

A

support, storage of minerals, storage of lipids, blood cell production, protection, leverage

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2
Q

bones are classified by

A

shape, internal tissue organization, bone markings

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3
Q

long bones

A

long and thin; found in arms, legs, hands, feet, fingers, toes

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4
Q

flat bones

A

thin with parrallel surfaces; skull, sternum, ribs, scapulae

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5
Q

irregular bones

A

complex shapes, spinal vertebrae, pelvic bones

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6
Q

short bones

A

small and thick; ankle and wrist bones

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7
Q

sesamoid bone

A

not directly connected to other bones, develop inside tendons; patella

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8
Q

depressions or grooves

A

points of attachment

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9
Q

projections

A

where tendons and ligaments attach; articulation with other bones

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10
Q

tunnels

A

where blood and nerves enter bone

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11
Q

long bone structure (3 parts)

A

diaphysis, epiphysis, metaphysis

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12
Q

diaphysis

A

the shaft; heavy wall of compact bone, central space called medullary cavity (marrow)

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13
Q

epiphysis

A

wide part at ends, articulation with other bones, mostly spongy bone covered with compact bone

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14
Q

metaphysis

A

where diaphysis and epiphysis meet; hyaline cartilage until adulthood

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15
Q

flat bone structure

A

sandwich of spongy bone between two layers of compact bone

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16
Q

diploe

A

spongy bone in the cranium

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17
Q

membranes of bone

A

periosteum, endosteum

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18
Q

periosteum

A

outer fibrous layer with inner osteogenic layer: osteoblasts, osteoclasts, osteogenic cells (stem cells)

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19
Q

periosteum (nutrient and securement)

A

nerve fibers, blood vessels and lymphatic vessels via nutrient foramina; secured to bone by collagen and sharpey’s fibers

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20
Q

endosteum

A

delicate membrane on internal surface of bone, osteoblasts and osteoclasts; covers trabeculae and lines canals

21
Q

red marrow cavities of adults

A

trabecular cavities of heads of femur and humerus and diploe of flat bones

22
Q

red marrow cavities of children

A

medullary cavities and all spaces in spongy bones

23
Q

osteocytes

A

Bone Maintainers: mature bone cells that maintain the bone matrix, live in lacunae, monitor and maintain mineral content and repair damage bone

24
Q

osteoblasts

A

Bone Makers: immature bone cells that secrete matrix compounds (osteogenesis); if surrounded by bone they become osteocytes

25
osteoid
matrix produced by osteoblasts, but not yet calcified to form bone
26
osteoclasts
Bone Breakers: secret acids and protein digesting enzymes, giant multinucleate cells, dissolve bone matrix and release stored minerals (osteolysis); derived from stem cells that produce macrophages
27
Osteoprogenitor Cells
mesenchymal stem cells that divide to produce osteoblasts, located in the endosteum and inner cellular layer of periosteum; assist in fracture repair
28
homeostasis
bone making must balance with bone recycling
29
Anatomy of compact bone (osteon) 5
lamellae, central canal, perforating canal (volkmann), lacunae, canaliculi
30
Anatomy of spongy bone
open network of trabeculae, irregularly arranged lamellae, osteocytes and canaliculi; no osteon or central canal; red or yellow marrow
31
organic composition of bone
osteogenic, blasts, clasts, cytes, osteoid, proteoglycans, glycoproteins, collagen fibers
32
inorganic composition of bone
hydroxyapatites: mineral salts (65% of mass) mainly calcium phosphate,
33
mineral salts
responisble for hardness and resistance of compression
34
intramembranous ossification
from fibrous membranes (mesenchyme); flat bones; 1) mesench cluster 2) diff in to osteoprogen 3) divide to become osteoblasts
35
endochondral ossification
originate as hyaline cartilage; most bones except flat, 6 main steps:
36
interstitial vs apositional
increase the length vs. increase the thickness, remodeling of surfaces
37
epiphyseal plate cartilage 4 zones
proliferation (cartilage dividing), hypertrophic (increase size), calcification, ossification
38
hormones
growth hormones, thyroid hormones, testosterone and estrogen
39
wolfs law
greater stress= more bone deposition; support: handedness, curved bones, trabeculae, bony projections
40
bone remodeling
osteoclasts break down bone: lysosomal enzymes and acids; osteoblasts deposit; replaces minerals, recycles and renews matrix;
41
effects of excercise on bone
bones adapt to stress, stress makes thicker and stronger
42
bone nutrition
calcium, phosphate salts, small amt of magnesium, fluoride, iron and manganese; hormone calcitrol; vitamin d
43
calcium
most abundant mineral in the body, ions are vital to membranes, neurons, muscle cells (heart)
44
calcium homeostasis
calcitonin/thyroid (too much) and parathyroid hormone (too little), controls storage (bones) absorption (Dig) and excretion (kid)
45
osteomalacia and rickets
when calcium salts are not deposited, caused by vit d or calcium deficiency
46
osteopenia
general bone loss, thinner and weaker with age, starts 30-40, women lose 8% per decade, men 3%; epiphyses, vertebra and jaws mostly
47
osteoporosis
severe bone loss, over 45, 29% of women, 18% men
48
osteoporosis treatment
ca, vD, fluoride supplements; weight bearing excercise, hormone replacement therapy slows loss