booby pathology Flashcards
(47 cards)
milk line
area along body from nipple to vulva area; any breast cancer can happen here along with extra nipples etc..
galactorrhea
milk production outside of lactation; NOT a Sx of BC; causes: nipple stimulation, prolactinoma of ant. pituitary, drugs
acute mastitis
S. aureus most common; bacterial; assoc. with breast feeding
acute mastitis presentation
warm erythematous breasts with pus discharge
acute mstitis Tx
continued breast feeding to facilitate drainage and dicloxacillin
periductal mastitis
inflammation of aubareolar ducts; usually seen in smokers (causes a relative vit A def.) causing a metaplasia to squamous cell in tubule then leading to blockage;
periductal mastitis presentation
subareolar mass with nipple retraction
mammary duct ectasia
inflammation of the duct and may dilate; this dilate can lead to debris build up then leading to a green brown nipple discharge; Bx shows chronic inflammation with plasma cells
mammary duct ectasia usually arise in
multiparous post menopasual women
fat necrosis of breast
necrosis of breast fat; usually related to trauma (doesnt have to be serious like a fight, it could be from a softball); mass on exam or calcification on mammography; Bx shows necrotic fat with assoc. calcifications and giant cells
fibrocystic change of breast
most common change in premenopausal woman; gross inspect has a blue domed appearance
fibrocystic change of breast presentation
vague changes to breast; “lumpy breast”; usually Upper outer quadrant
fibrocystic change is
benign; but other thcnages can indicate possibility for carcinoma
what changes in fibrocystic change of breast mean possible invasive carinoma risk
ductal hyperplasia and sclerosing adenosis (multiple more glands and fibrosis assoc with it); atypical hyperplasia
what changes in fibrocystic change of breast do not mean risk of invasive carcinoma
fibrosis, cysts, apocrine metaplasia
if seeing the fibrocystic chganges that increase risk for invasive carcinoma then that increases risk for which breast
both even if unilateral
intraductal papilloma
papillary growth that usually into the large duct; HAS BOTH fibrovascular projections lined by epi and myoepithelial cells; bloody nipple discharge in premenopausal woman; MUST distinguish from papillary carcinoma
distinguish between intraductal papilloma and intraductal carcinoma
carcinoma is usually post menopausal; carcinoma has NO myoepithelial cells
fibroadenoma
tumor of fibrous tissue and glands; most common benign neoplasm of breast; most common is premenopasual woman; estrogen sensitive; NO increased risk for carcinoma
fibroadenoma histo
well circumscribed, mobile marble like mass;
Phyllodes tumor
fibroadenoma like tumor with overgrowth of the FIBROUS component; leaf like projections seen; POST menopausal women; can be malignant
Cancer is most common usually in
POST menopasual
risk factors for BC
female gender, age (more often POST menopasual), early menarche/late menopause, obesity, atypical hyperplasia, first-degree relative with breast cancer
ductal carcinoma in-situ (general description)
maligannt cells in duct that are bound to duct;
