BRAIN CELLS Flashcards

(39 cards)

1
Q

What are the three main purposes of neurons?

A

Sensation, integration, and action.

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2
Q

What is the function of sensory neurons?

A

To carry information from the senses to the CNS.

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3
Q

What is the function of motor neurons?

A

To carry commands from the CNS to muscles and organs.

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4
Q

What is the function of interneurons?

A

To connect and integrate neurons within the CNS.

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5
Q

What is the resting membrane potential?

A

The difference in electrical charge across the neuron membrane at rest (~ -70mV).

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6
Q

What maintains the resting membrane potential?

A

Sodium-potassium pump and ion distribution.

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7
Q

What ion is more concentrated inside the cell at rest?

A

Potassium (K+).

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8
Q

What ion is more concentrated outside the cell at rest?

A

Sodium (Na+).

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9
Q

What does the sodium-potassium pump do?

A

Pumps 3 Na+ out and 2 K+ into the cell.

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10
Q

What is depolarisation?

A

A decrease in membrane potential (more positive).

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11
Q

What is hyperpolarisation?

A

An increase in membrane potential (more negative).

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12
Q

What is an action potential?

A

A brief electrical charge that travels down the axon.

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13
Q

What triggers an action potential?

A

Depolarisation reaching the threshold.

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14
Q

What is the threshold potential?

A

Around -55mV.

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15
Q

What happens during the refractory period?

A

The neuron cannot fire another action potential.

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16
Q

What is saltatory conduction?

A

The jumping of action potentials between nodes of Ranvier.

17
Q

What is the function of astrocytes?

A

Support, nourish, clean debris, and form the blood-brain barrier.

18
Q

What is the blood-brain barrier?

A

A semi-permeable membrane that protects the brain from harmful substances.

19
Q

What is the main function of microglia?

A

Immune defense in the CNS.

20
Q

What is the role of oligodendrocytes?

A

Form the myelin sheath in the CNS.

21
Q

What is the role of Schwann cells?

A

Form the myelin sheath in the PNS.

22
Q

What is the difference between CNS and PNS?

A

CNS: brain and spinal cord; PNS: all other nerves.

23
Q

What is myelin?

A

A fatty substance that insulates axons and speeds up signal transmission.

24
Q

What is synaptic pruning?

A

The removal of unnecessary synapses.

25
What is phagocytosis?
The process by which glial cells clear debris.
26
What is the role of calcium in astrocytes?
It facilitates chemical signalling.
27
What disease is associated with glial malfunction?
Multiple sclerosis (MS).
28
What is multiple sclerosis?
A disease caused by demyelination due to glial cell failure.
29
What glial cells are involved in neuropathic pain?
Schwann cells, microglia, and astrocytes.
30
What is electrostatic pressure?
The force between charged molecules.
31
What is diffusion in neurons?
Movement of ions from high to low concentration.
32
What are afferent neurons?
Sensory neurons carrying signals to the CNS.
33
What are efferent neurons?
Motor neurons carrying signals from the CNS.
34
What is a synapse?
The gap between neurons where communication occurs.
35
What neurotransmitter is involved in muscle contraction?
Acetylcholine (ACh).
36
What is the function of dendrites?
To receive signals from other neurons.
37
What is the axon hillock?
The area where action potentials are initiated.
38
What happens when a neuron is polarised?
It has a negative charge inside relative to the outside.
39
What happens when a neuron is depolarised?
The inside becomes less negative.