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Cancer, Skin & Infection > Breast > Flashcards

Flashcards in Breast Deck (11):
1

What is the most common cause of malignant breast lump?

Invasive ductal carcinoma
Invasive lobular carcinoma

2

Name three causes of benign breast lumps?

Fibroadenoma
Cyst (may be painful)
Abscess (painful, hot and swollen breasts)

3

What may breast dimpling imply?

May imply invasion of cancer into underlying musculature
May imply pulling on ligaments of breast by the cancer

4

What are the three stages of triple assessment?

Clinical examination
Imaging (USS / MMG)
Biopsy (FNA)

5

Triple negative breast cancer is negative for which three immunological markers?

HER2
ER2
PR

6

Indications for mastectomy instead of a wide local excision?

Multifocal

Local reoccurrence after wide local excision

Invasive cancer of >4cm

7

What class of drug is tamoxifen and what are the side effects?

Anti-estrogen

Increased risk of DVT
Menopausal symptoms
Endometrial thickening (polyps, hyperplasia, cancer)
Cataracts

8

What is lactational mastitis?

What is it caused by?

inflammatory condition of the interlobular connective tissue that affects 10% of breastfeeding women. The main underlying cause is milk stasis caused by overproduction or insufficient removal of milk. It may be infectious (retrograde spread of commensal organisms via a milk duct or a traumatised nipple) or non-infectious

9

What factors predispose someone to lactational mastitis?

Baby not attaching to breast
Nulliparity
Tight bra
Use of dummy or bottle

10

Which antibiotics are preferred in breast feeding mothers?

Penecillins

11

What are Montgomery tubercles?

sebaceous glands in the areola around the nipple. They are a normal finding, but may become more pronounced during pregnancy.