Breast Mass/CA Flashcards Preview

Reproductive system (inpt) > Breast Mass/CA > Flashcards

Flashcards in Breast Mass/CA Deck (23)
Loading flashcards...
1

Causes of Breast MAsses

-fibrocystic changes/cysts
-fibroadenoma
-intraductal papilloma
-fat necrosis
-abscess
-malignancy

2

evaluation if younger than 30 years

-charachteristics of a cyst: monitor x 1-2 menstural cycles or aspirate

3

if younger than 30, breat mass persists or more suspicious?

-US

4

if US neg in woman under 30>

observe q 3-6 mnth, considered mammogram

5

if simple cyst

-reassure, observe or aspirate

6

if complex cyst?

mammogram

7

if solid mass?

mammogram:
C3- short ter f/u w/ imaging
C4/5-bx

8

if age > 30 yo?

unilateral dx mammo and US

9

if >40 yo?

can get bilateral mammo

10

Breast Ca

most common female malignancy and the second leading cause of death from CA in women

11

RF for BCA?

most women have no identifiable RF-

being women, increasing age

-BRCA1 AND 2, associated w. 5-10% of the pts, but only seen in 1% of the population

12

associated rf for BCA?

nulliparity, early menarche, late menopause, long-term estrogen or radiation exposure, delayed childbearing

13

what about relatives w/ BCA?

women w/ first degree relatives are at increased risk, especially if the CA was premenopausal or bilateral

14

relation to endometrial ca?

Breast CA incrases the risk of endometrial and vice versa

15

what is the most common type of breast ca?

ductal carcinoma (50-80%); the rest are lobular carcinomas

16

what may presidpose one to breast ca?

lobular CIS and atypical ductal hyperplasia

17

what is Paget's dz?

ductal carcinoma presenting as an excematous lesion of the nipple

18

what is a feature of invasive lobular carcinomas and 2/3 of ductal carcinomas?

estrogen-receptor positive

19

what are the CF of breast ca?

presents as a single, nontender, firm, immobile mass

-45% occur in the upper outer quadrant, 25% under the nipple and areola

20

what type can be detected early, but w/ no palpable mass?

early carcinoma

21

what are rarer presentations of breast ca?

include nipple discharge or retraction,
-dimpling,
-breast enlargement or shrinkage,
-skin thickening or peau d’orange skin,
-eczematous changes, breast pain,
-fixed mass,
-axillary node enlargement, ulceration
- arm edema
- palpable supraclavicular nodes

22

dx of BCA

-combo of PE, mammo, and fine-needle/stereotactic core needle bx
-US and excisional bx may be indicated
-bx need to undergo estrogen and progesterone receptor analysis and histologic analysis

23

tx of BCA

-stage before tx
o Breast conservation therapy (lumpectomy), modified radical mastectomy, and partial mastectomy have equivalent survival rates when surgery is followed by radiation therapy
o Adjuvant chemotherapy and/or hormonal manipulation benefit some women
o Tamoxifen is used to treat women with estrogen receptor-positive disease and postmenopausal women