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Reproductive system (inpt) > Menopause > Flashcards

Flashcards in Menopause Deck (14)
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1

meopause

no menses for >1 year; last menses,

2

perimenopause

is the time surrounding it

3

what is the mean age of natural menopause?

51.5 yrs, 95% of women stop mensturating btw 44 and 55 years

4

what is associated w/ early menopause?

smoking!

5

premature menopause?

cessation of menses before age 40

6

what hormones are still circulating after menopause?

-testosterone
-androstenedione
-estrone

7

what is the first sign of menopause?

menstraul irregularities

8

CF of menopause

-hot flashes and vasomotor instability (usually resolve in 2-3 yrs; 3-6 wks w/ estrogen replacement therapy)

-urogenital atropy: may cuase poor vaginal lubrication, dyspareunia, dysuria, urge incontinence, pelvic relaxation, atrophic cystitis, easy bleeding

-caruncles, leucorrhea (whitish-discharge)

-accelerated bone loss
-changes in sleep cycles

-skin thins, becomes less elastic, facial hair may incrase, hair loss, brittle nails

9

dx of menopause?

FSH > than 30 mIU/ML

10

tx of menopause?

combined hormone replacement therapy

11

what are some ADR and associations of CHRT

increased risk for CVD, Breast CA, congnitive changes, migraine, gallbladder dz

12

what are CI for HRT

undix vaginal bleed, acute vascular thrombosis, hx of estrogen dependent tumores

13

what else can be used for other isseus?

Ca/Vit D suppliments, bisphosphonates, SERMs, calcitonin

14

what about unopposed strogen administration?

endometrail cancer