Breast Pathology Flashcards
Most common cancer in women in the US?
Breast cancer - if post menopausal: invasive ductal
Most common benign breast tumor?
Fibroadenoma
Most common malignant breast tumor?
Infiltrating ductal carcinoma
Blue dome cyst in the breast?
Fibrocystic change
Treatment for ER+ breast CA?
Tamoxifen
What disease is at hand: red, itchy, swollen rash on the areola and nipple.
Paget disease
Resembles fibroadenoma in mammogram but much larger-leaf like projections… may become malignant.
Phyllodes tumor
Fills ductal lumen - arises from ductal atypia. Often seen as early microcalcifications on mammography. Early malignancy without basement membrane penetration.
Ductal carcinoma in situ
Ductal, central necrosis: subtype of DCIS…
Comedocarcinoma
Results from underlying DCIS or invasive breast cancer. Eczematous patches on nipple. Histology: large cells in epidermis with clear halo. Presence on vulva does not suggest underlying malignancy.
Pages disease
Epithelial and myoepithelial cells lining fibrovascular cores in a cyst wall or duct. It’s the MCC of bloody nipple discharge.
What breast pathology is being described?
Intraductal papilloma
Usually presents without breast masses or skin changes.
