Female Non-Neoplasm Pathology

Question 1

This syndrome may present with primary amenorrhea (due to lack of uterine development) in females with fully developed secondary sexual characteristics (functional ovaries).

Answer 1

Müllerian agenesis (Mayer-Rokitansky-Küster-Hauser Syndrome).

Question 2

Name the components of HELLP syndrome. What is seen in a blood smear?

Answer 2

H-Hemolysis
EL-Elevated liver enzymes
LP-Low Platelets

A manifestation of severe preeclampsia. —> shows Schistocytes

Question 3

What are the complications of HELLP syndrome?? What is the treatment?

Answer 3

DIC, hepatic subscapular hematomas, rupture, leading to severe hypotension.

Treatment is: immediate delivery

Question 4

What are the pathologies associated with XO (Turner’s Syndrome)?

Answer 4

Ovarian dysgenesis, shield chest, bicuspid aortic valve, coarctation of the aorta, lymphatic defects (causing edema), and horseshoe kidney. MCC of primary amenorrhea, no Barr body.
Menopause before menarche.