Breast & Womens Health Flashcards

(46 cards)

1
Q

Features of bloody nipple discharge associated with malignancy

A
  1. Spontaneous
  2. Unilateral
  3. Localized to a single duct
  4. Present in women >40 years pf age
  5. Bloody
  6. Associated with a mass
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2
Q

Benign milk filled cysts that occur almost exclusively in lactating women characterized by a triad of secretory breast epithelium, prolactin stimulus , and ductal obstruction.

A

Galactocele

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3
Q

Involves resection of the primary breast cancer with a margin of normal appearing breast tissue, adjuvant radiation therapy, and assessment of regional lymph node status.

A

Breast conservation therapy

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4
Q

Breast conservation treatment for T2 N0 M0 breast carcinoma must have __________?

A

Adjuvant radiotherapy

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5
Q

Absolute contraindications to breast conservation surgery?

A
  1. Prior radiotherapy
  2. Pregnancy ( 1st to 2nd trimester)
  3. Persistently positive margins
  4. Multicentric lesions
  5. Diffuse microcalcifications
  6. Connective tissue disorders
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6
Q

Management of breadt cancer during pregnancy?

A

1st & 2nd trimester:
1. Modified Radical Mastectomy

3rd trimester
1. Lumpectomy with axillary node dissection ( if adjuvant radiotherapy is deferred until after delivery)

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7
Q

Triad of Carcinoid Syndrome?

A

Flushing
Diarrhea
Cardiac involvement

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8
Q

Drugs used in the management of Cushings disease?

A

Aminoglutethimide
Ketoconazole
Metyrapone

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9
Q

Percentage of women with BRCA1 mutation developing breast cancer before age 70.

A

55-65% of women

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10
Q

Diagnostic features of MEN2B ?

A
  1. MTC
  2. Pheochromocytoma
  3. Multiple neuromas
  4. Long narrow face , retrognathia, highly arched palate
  5. Marfanoid habitus
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11
Q

Reddish tender , warm breast in a nursing mother is most likely a case of?

A

Epidermic puerperal mastitis

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12
Q

Which of the following is a characteristic of pathologic nipple discharge ?

A

Spontaneous and non-bloody

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13
Q

Most widely used and accurate modality for preoperative localization of abnormal parathyroid gland is _________.

A

Technitium -sestamibi scan

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14
Q

Which statement regarding the emissary vein is correct?

A

It is located in the loose areolar tissue

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15
Q

Lateral border of the breast found at the anterior axillary line

A

Axillary tail of Spence

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16
Q

_________________ are found deep to the pectoralis minor muscle

A

Breast lymphatics

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17
Q

Risk factors for Zuka’s disease , also known as recurrent periductal mastitis

A

Cigarette smoking

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18
Q

Venous plexus that extends from the base of the skull to the sacrum?

A

Batson vertebral plexus

Provides a route for breast cancer metastasis.

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19
Q

Risk factors for Breast Cancer? (6)

A
  1. Increased exposure to estrogen
  2. Radiation exposure
  3. Increased alcohol intake
  4. High fat diet
  5. Prolonged use of OCPs and HRT
  6. Family history of breast CA
20
Q

Age of start annual screening mammogram

21
Q

Age of start of annual screening mammography?

22
Q

Most common presentation of breast cancer?

A

Palpable mass

23
Q

Most common first site of distant spread?

A

Bone 51%
Lung 17%
Brain 16%
Liver 6%

24
Q

Diagnostic used to evaluate dense breasts and for BIRADS 0 mammogram results?

A

Breast ultrasound

25
Minimum number of nodes required for adequate staging of breast cancer?
10 nodes
26
Removal of the entire breast and axillary lymph nodes?
Modified radical mastectomy
27
Management of breast cancer during 1st and 2nd trimester of pregnancy?
Modified radical mastectomy
28
Cells found in the epidermis of the nipple that is possible source of Pagets diasease of the nipple?
Toker cells
29
Most striking and consistent symptom of esophageal rupture.
Pain
30
Phase of caustic esophageal injury when the esophagus is weakest?
2nd phase (ulceration and granulation)
31
Which of the following characterizes endometrial hyperplasia?
Caused by estrogen secreting tumors like granulosa cell tumor
32
Surgery as the primary modality of treatment for cervical cancer is generally recommended for what stage of the disease?
I
33
Virilizing adrenal tumors secretions
Dehydroepiandrosterone Androstenedione Testosterone and Estrogen
34
Which of the following characterizes endometrial hyperplasia?
Caused by estrogen secreting tumors like granulosa cell tumor
35
Most common gynecologic cancer
Cervical cancer
36
Hormone responsible for lobular development of the breast ?
Progesterone
37
Hormone responsible for ductal development of the breast ?
Estrogen
38
Hormone regulates release of estrogen and progesterone?
LH/ FSH
39
High risk BRCA mutation carriers do mammogram , TVS, CA 125 yearly beginning at what age ?
25 yo
40
Microscopic finding of invasive lobular carcinoma?
Indian file configuration : small cells arranged on single file orientation.
41
Baseline mammogram starts at what age?
35 yo
42
Annual mammogram begins at what age?
40 yo
43
Breast surgery: Resection of primary breast cancer + Margin of normal appearing breast tissue + Assessment of regional lymph nodes status.
Breast Conservation
44
Breast surgery: Resection of Medial/ Lateral Pectoral Nerves + Long Thoracic Nerve+ Thoracodorsal Nerve + Pectoralis Major & Minor + All LN + All Breast.
Radical Mastectomy
45
Same as Radical Mastectomy except all nerves are spared , level III LN spared , Pectoralis **Major** is spared.
Modified Radical Mastectomy
46
Spared in Modified Radical Mastectomy? (3)
1. All nerves are spared : Long thoracic, Medial / Lateral Pectoral Nerves, Thoracodorsal Nerve 2. Level III LN 3. Pectoralis Major