Brpt 04 Flashcards

(61 cards)

1
Q

Hypoxia

A

Lack of oxygen at the tissue level; does not meet cellular needs

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2
Q

Hypoxemia

A

Lack of oxygen in the arterial blood

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3
Q

Hyperoxia

A

Increased levels of oxygen to the tissues usually due to the use of supplement O2

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4
Q

Hypocapnea (hypocarbia)

A

Decrease in CO2 in the blood

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5
Q

Hypercapnea (hypercarbia)

A

Increase in CO2 in the blood

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6
Q

Cyanosis

A

Bluish tinge of skin and mucous membrane visible when you have 5 Gm/100 ml or 5 % of blood of dissociated hemoglobin

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7
Q

Secondary polycythemia

A

Increased production of RBCs. Compensatory mechanism to decreased levels of oxygen in the blood

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8
Q

A/C membrane has three main barriers:

A

Alveolar epithelium
Interstitial space and its structures
Capillary endothelium

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9
Q

Where is the highest CO2 level

A

In the venous blood

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10
Q

Hypoxemia aka hypoxic hypoxia

A

In adequate delivery of oxygen to the lungs or from the lungs got the blood

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11
Q

Causes of hypoxemia (hypoxic hypoxia)

A

Hypoventilation
High altitude
Shunt
V/Q mismatch

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12
Q

Does Hypoxemia (hypoxic hypoxia) respond to oxygen therapy?

A

Yes except for shunts because of no blood flow

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13
Q

Anemic Hypoxia

A

Hemoglobin deficiency

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14
Q

Anemic Hypoxia causes

A

Carbon monoxide poisoning, loss of hb

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15
Q

Does Anemic hypoxia respond well to oxygen therapy?

A

Yes

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16
Q

Circulatory hypoxia

A

Stagnant or hypoperfusion or low blood flow

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17
Q

Circulatory hypoxia causes

A

Ischemia, cardiac pump failure, shock

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18
Q

Does Circulatory hypoxia respond to oxygen therapy?

A

Yes as long as the pump is working. Do not withhold oxygen from patient

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19
Q

Histotoxic hypoxia (dysoxia)

A

Poisoning of the cellular oxygen utilization mechanism has occurred

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20
Q

Histotoxic hypoxia (dysoxia) example

A

Cyanide poisoning

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21
Q

Does histotoxic hypoxia (dysoxia) respond to oxygen therapy?

A

No

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22
Q

Acute hypoxia sign/symptoms

A

Tachypnea, increase depth of rr, tachycardia, arrhythmia, confusion

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23
Q

Chronic hypoxia signs/symptoms

A

Increased AP diameter on CXR and secondary polycythemia

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24
Q

Indications for oxygen use

A

PaO2 <60mmHg or SaO2 <90%

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25
When hypoxia is suspected
severe trauma, increase work of heart and breathing, acute myocardial infarction
26
Possible hazard/side effect of oxygen use
Absorption atelectasis and oxygen toxicity
27
How does oxygen toxicity occur
Increased FiO2
28
PIO2 definition
Partial pressure of inspired oxygen
29
PAO2 definition
Partial pressure of oxygen in the alveoli
30
PaO2 definition
Partial pressure of oxygen in arterial blood
31
PvO2 definition
Partial pressure of oxygen in mixed venous blood
32
SaO2 definition
Oxygen saturation of hemoglobin in arterial blood
33
SvO2 definiton
Oxygen saturation of hemoglobin in mixed venous blood
34
PvCO2 definition
Partial pressure of carbon dioxide in mixed venous blood
35
PACO2 definition
Partial pressure of carbon dioxide in the alveoli
36
PICO2 definition
Partial pressure of inspired carbon dioxide
37
PACO2 definition
Partial pressure of carbon dioxide in arterial blood
38
PIO2 normal value
159 mmHg
39
PAO2 normal value
99-100 mmHg
40
PaO2 normal value
80-100 mmHg
41
PvO2 normal value
40 mmHg
42
SaO2 normal value
95-97.5 %
43
SvO2 normal value
75%
44
PvCO2 normal value
45 mmHg
45
PACO2 normal value
40 mmHg
46
PICO2 normal value
.23 mmHg
47
PACO2 normal value
35-45 mmHg
48
What do peripheral chemoreceptors respond to
PaO2 <60 mmHg (decreased oxygen in arterial blood)
49
What does the body use to regulate the respiratory cycle?
Oxygen chemoreceptors
50
Knocking out their hypoxic drive can occur as a result of?
Increased PaO2 (increased oxygen in arterial blood)
51
Retinopathy of Prematurity (ROP)
Increased PaO2 greater than 80 mmHg (oxygen in blood > 80)
52
Bronchopulmonary Dysplasia (BPD)
Fibrotic tissue damage caused by high levels of INHALED oxygen (FiO2)
53
BPD vs ROP
BPD = increase of FiO2, ROP = increase of PaO2
54
Absorption Atelectasis
Collapse of alveoli because of high levels of inhaled air (FiO2 increase) causing the elimination of N2 from the lung
55
Affinity when O2 dissociation curve shifts RIGHT
Decrease
56
Affinity when dissociation curve shifts LEFT
Increased
57
If the oxyhemoglobin curve shifts to the RIGHT identify the factors that can affect it
Decrease PH, increase temperature, increased 2,3 DPG, increase PaCO2
58
If the oxyhemoglobin curve shifts to the LEFT identify the factors that can affect it
Increase PH, decrease in temperature, decrease 2,3 DPG, decrease in PaCO2
59
a patient is hyperventilating and receives oxygen therapy we should expect cardiac output to
Decrease
60
Arterial blood gas values reflect gas exchange at the _______ level
Pulmonary
61
Venous blood gas values reflect gas exchange at the _________ level
Tissue