Brucellosis

Question 1

can Brucellosis survive an acidic environment

Answer 1

NO (dies at pH 3.5)

Question 2

Brucellosis survives cold environment

Answer 2

TRUE (preferred)

Question 3

most widespread Brucellosis

Answer 3

B. abortus

Question 4

Brucellosis spp that is NOT zoonotic

Answer 4

B. ovis (sheep)

Question 5

which environments (2) do Brucella prefers

Answer 5

1) terrestrial
2) marine

Question 6

Brucellosis where diff organs are affected

• bone & joints
• CNS
• eyes
• cardiovascular
• respiratory
• reproductive

Answer 6

chronic brucellosis

Question 7

can Brucella cause abortion in humans as well?

Answer 7

YES

Question 8

how many times can Brucella cause abortion in:

ruminants =
dogs =

Answer 8

ruminants = once (infertile na)
dogs = recurring

Question 9

Brucella causes these 2 disease in HORSES

Answer 9

1. Fistulous withers
2. Poll evil

Question 10

does Brucella cause death?

Answer 10

RARE

except in fetus

Question 11

what organ can Brucella persist for longer period of time?

Answer 11

lymph nodes

Question 12

is the animal infected with Brucella condemned/slaughtered agad?

Answer 12

YES

Question 13

risk factor for Brucella?

young or old?
male or female?
hot or cold?
agroecology?

Answer 13

old
female
cold
dry climate

Question 14

is Brucella a neglected zoonoses?

Answer 14

YES

Question 15

Brucella is risk group?

Answer 15

3 (BSL 3)

Question 16

gold standard for Brucellosis?

Answer 16

bacterial culture

Question 17

Brucella spp with rough LPS

[ ams ]

Answer 17

B.
abortus
melitensis
suis

Question 18

Brucella spp with smooth LPS

[ oc ]

Answer 18

B.
ovis
canis

Question 19

Serologic tests like:
1) Brucellin skin test
2) Rose Bengal tes

should be tested how many times?

Answer 19

2x

Question 20

relies on “cell-mediated” immunity for antibody production

Answer 20

Brucellosis

Question 21

tests for Brucellosis that uses methylene blue (+ is uniform blue solution)

Answer 21

Milk Ring test

Question 22

treatment of Brucella for more than 8 y/o & adults?

Answer 22

doxycycline (PO)
gentamicin (IM)

Question 23

treatment of Brucella for less than 8 y/o ?

Answer 23

trimethoprim sulfamethoxazole (PO)
gentamicin (IV / IM)

Question 24

treatment of Brucella for pregant humans?

Answer 24

trimethoprim sulfamethoxazole (PO)
rifampicin (PO)

Question 25

treatment of Brucella for animals?

Answer 25

long term antibiotics with
• doxycycline
• gentamicin

Question 26

Brucella may cross react with

[ FEYV ]

Answer 26

Francisiella
E. coli
Yersinia
Vibrio

Question 27

vaccination and route for B. abortus?

(antibody production)

Answer 27

S19 vaccine (SC)

Question 28

vaccination and route for B. melitensis?

Answer 28

Rev-1 vaccine (SC)

Question 29

RB51 vaccine route?
(cell-mediated immunity)

Answer 29

intraconjunctival route

Question 30

most pathogenic Brucella?

Answer 30

B. melitensis (1-10 infectious dose)

Question 31

3 places with NO brucella

Answer 31

1. Japan
2. Canada
3. New Zealand

Question 32

How long should you pasteurize milk to kill Brucella?

Answer 32

63C for 30 mins

Question 33

only 1 with no CAT as accidental host

Answer 33

B. melitensis

Question 34

only 1 with no CAMEL & HORSE as accidental host?

Answer 34

B. canis