Brucellosis Dem Dem Flashcards
(30 cards)
What animals does brucellosis affect
Farm animals( cattle sheep swine goats
How do they generally acquire the disease
Through direct contact with infected animals , drinking unpasteurized milk and whatnot
What are the symptoms
Flu like
Fever weakness malaise and weight loss
Which groups of people are at greater risk
People who work in labs containing such bacteria , also abbatoirs and their employees
About the Brucella spp
Gram n or p
Negative
What is the shape
Coccobacillus
Respiration
Facultative intracellular
This spps presents with environment persistence?
T ( harsh weather drying, freezing , dust soil)
Clinical presentation
What is perculiar about their existence
Flu like symptoms .. muscle pain joints pain
Fatigue
Note that some signs and symptoms may persist and others may never go away or reoccur
Incubation period
Variable
5 days to three months
It does not affect any organ or organ system
T or false
Isolation of organsism is by what specimen
Blood, bone marrow
Other diagnosis
Serum agglutination test
Immunofluorescence
PCR
Treatment
Doxycycline
Streptomycin
Rifampicin
What do you use in pregnancy
Rifadin + co trimoxazole
Talk about causes involving the CNS
Treat 6-9 months
Same for endocarditis
Prognosis
If treated
Case fatality rate if the untreated
% of relapsed cases and why
Rarely Fatal if treated
2%
5% - failure to complete treatment and superimposed infections that require surgical intervention
Meaning it has a good prognosis
What is the major cause of death of this disease
Endocarditis and meningitis
Is there is a vaccine for humans and animals
No human vaccine but there is a vaccine for young goats and sheep and calves
What is the causative organism for meloidosis
Burkholderria pseudomallei
Gram stain and is prevalent in which country has
Negative … South East Asia
What is it characterized by
Sepsis and abscess formation
Mortality rate and who does it affect
40%
People who are in regular contact with soil and water
It is a seasonal disease prevalent in which season
Rainy season