Buzzwords Flashcards

(55 cards)

1
Q

Brushfield spots in the iris

A

Down syndrome

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2
Q

Single palmar crease

A

Down syndrome

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3
Q

Barr body

A

Klinefelter

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4
Q

Gynecomastia

A

Klinefelter

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5
Q

Silver-white scaly lesion

A

Psoriasis

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6
Q

Neutrophils in the stratum corneum

A

Psoriasis

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7
Q

multiple minute bleeding points

A

Psoriasis

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8
Q

edema between keratinocytes

A

eczema

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9
Q

Undulant epidermal hyperplasia

A

verrucae (common to both forms)

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10
Q

Blue-gray elastic fibers

A

actinic keratosis

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11
Q

Keratin pearls

A

squamous cell carcinoma

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12
Q

elevated serum creatine kinase

A

muscular dystrophy

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13
Q

dystrophin

A

Duchenne or Becker muscular dystrophy

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14
Q

pseudohypertrophy of calves

A

Duchenne or Becker muscular dystrophy

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15
Q

red granular stuff in sarcoplasm (ragged red fibers)

A

mitochondrial myopathy

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16
Q

para-crystalline “parking lot inclusions” in the cristae of mitochondria

A

mitochondrial myopathy

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17
Q

PAX3-FKHR gene fusion

A

rhabdomyosarcoma

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18
Q

its worse to be a man

A

melanoma

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19
Q

tadpole and strap cells

A

rhabdomyosarcoma

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20
Q

a1 or a2 type 1 collagen mutation

A

osteogenesis imperfecta

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21
Q

Blue sclera

A

Osteogenesis imperfecta TYPE 1!

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22
Q

Point mutation (gain of function) in FGFR3

A

Achondroplasia

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23
Q

Increased osteoclasts

A

Type 1 (postmenopausal) osteoporosis

24
Q

Dowager’s hump

A

aka kyphosis. Osteoporosis

25
Decreased osteoblasts
Type 2 (senile) osteoporosis
26
diffuse pain, aspirin doesn't help
osteoblastoma
27
aspirin helps
osteoid osteoma
28
central radiolucent nidus, rim of sclerotic bone
osteoid osteoma or osteoblastoma
29
elevated serum alkaline phosphatase
osteosarcoma
30
lifted periosteum --> Codman Triangle
osteosarcoma
31
monosodium urate crystals
gout
32
intraparenchymal vessel rupture
intracerebral hemorrhage
33
berry aneurysm
subarachnoid hemorrhage
34
middle meningeal artery rupture
epidural hematoma
35
kicked in the side of the head
epidural hematoma
36
fusiform and lenticular
epidural hematoma
37
stroke from hypertension
intracerebral hemorrhage
38
Pseudo-palisade arrangement of tumor cells
Glioblastoma multiforme
39
whorled pattern of concentrically arranged spindle cells
meningioma
40
psammoma bodies
meningioma
41
gamma globulin in CSF
MS
42
SORL-1
Late onset Alzheimer's
43
E2
good
44
E4
bad (Alzheimer's)
45
Presinilin-1
Early onset Alzheimer's
46
beta-amyloid
Alzheimer's
47
tau protein
neurofibrillary tangle - Alzheimer's
48
you get hit in the head, you think you are ok, then you die
epidural hematoma
49
2/3 have mutated RB gene, many also have mutated p53
osteosarcoma
50
acute hypocorticism
Waterhouse-Friderichsen syndrome (complication of bacterial meningitis)
51
HPV 2, 4
verruca vulgaris
52
HPV 3, 10
verruca plana
53
mitotic figures above the basal layer
psoriasis
54
thin or absent stratum granulosum
psoriasis
55
neutrophils in stratum corneum
psoriasis