C/I

Question 1

ALENDRONATE

C/I

Answer 1

GI inflammation
Oesophagus malfunction
Renal impairment
Hypocalcaemia
Pregnancy

Question 2

ATENOLOL

C/I

Answer 2

Asthma
Cardiogenic shock
Hypotension
Bradycardia
2/3rd* AV block
Uncontrolled heart failure

Question 3

ATRACURIUM

C/I

Answer 3

Electrolyte and fluid disturbances

Neuromuscular disorders

Question 4

BENDRO-FLUMETHIAZIDE

C/I

Answer 4

Addison’s disease
Hypercalcaemia
Hyponatraemia
Hyperuricaemia
Hepatic or renal impairment

Question 5

CEFUROXIME

C/I

Answer 5

Cephalosporin hypersensitivity

Question 6

CELECOXIB

C/I

Answer 6

Active GI bleeds
GI ulceration
CV disease
Inflam bowel disease
IHD/heart failure

Question 7

CHLORAMPENICOL

C/I

Answer 7

Acute Porphyrias

Question 8

CICLOSPORIN

C/I

Answer 8

Occular infections
Renal impairment
Malignancy
Uncontrolled hypertension or infection
Pregnancy/lactation

Question 9

CIPROFLOXACIN

C/I

Answer 9

Renal Impairment (alter dose)
Elderly
Children
Pregnancy
Lactation

Question 10

CO-AMOXICLAV

C/I

Answer 10

Risk of Superinfection
Penicillin Allergy
History of Cholestatic Jaundice
Liver Dysfunction

Question 11

DIAMORPHINE

C/I

Answer 11

Acute Respiratory Depression
Coma 
Head Injury
Raised ICP
Delayed Gastric Emptying

Question 12

DALTEPARIN

C/I

Answer 12

Infective Endocarditis
Haemophilia
Recent Cerebral Haemorrhage
Recent Eye/CNS Surgery

Question 13

DOBUTAMINE

C/I

Answer 13

Phaeochromocytoma

tumour of adrenal glands

Question 14

DOXAZOSIN

C/I

Answer 14

Micturition Syncope
Postural Hypotension
Anuria
Breast Feeding

Question 15

EPHEDRINE

C/I

Answer 15

Diabetes
Hypertension
Hyperthyroidism
IHD
Prostatic Hypertrophy
Pregnancy/Lactation

Question 16

ERYTHROMICIN

C/I

Answer 16

Electrolyte Disturbances
Myasthenia Gravis
Acute Porphyrias
Neonates <2 weeks

Question 17

ETHINYLESTRADIOL

C/I

Answer 17

Risk of Venous Thromboembolism or Arterial Disease
Migraine
Gallstones
Hepatic impairment

Question 18

FUROSEMIDE

C/I

Answer 18

Anuria
Coma + Liver cirrhosis
Hypokalaemia
Hyponatraemia	
Pregnancy

Question 19

IPRATROPIUM

C/I

Answer 19

Hypersensitivity to Atropine
Glaucoma
GI/Urinary Blockage

Question 20

LOPERAMIDE

C/I

Answer 20

High Fever
Blood in Stool
C. diff Infections
Active Ulcerative Colitis
Abdo. Distension

Question 21

METFORMIN

C/I

Answer 21

Risk of Lactic Acidosis

Kidney Disorders

Question 22

METHOTREXATE

C/I

Answer 22

Photosensitivity
Blood Disorders
Ulcerative Colitis
Peptic Ulceration

Question 23

OXYBUTININ

C/I

Answer 23

GI Obstruction
Myasthenia Gravis
Urinary Retention
Acute Porphyrias

Question 24

PARACETAMOL

C/I

Answer 24

Chronic Alcoholism
Chronic Dehydration
Chronic Malnutrition

Question 25

RAMIPRIL | C/I

Answer 25

``` Afro-Caribbean (less likely to respond) Renovascular Disease Hypovolaemia Hypotension Diabetes ```

Question 26

RIFAMPICIN | C/I

Answer 26

Acute Porphyrias Jaundice Liver Failure Pregnancy/Lactation

Question 27

RIVAROXIBAN | C/I

Answer 27

``` Active Bleeding Malignancies Oesophageal Varices Recent GI Ulcer Vascular Aneurysm ```

Question 28

SALMETEROL | C/I

Answer 28

Severe Pre-eclampsia

Question 29

SILDENAFIL | C/I

Answer 29

Retinal Disorders Recent MI/Stroke Hypotension Sickle-cell Anaemia

Question 30

SUXAMETHONIUM | C/I

Answer 30

Duchenne MD FH of Malignant Hyperthermia Hyperkalaemia Major Trauma/Burns

Question 31

TAMSULOSIN | C/I

Answer 31

Micturition Syncope | Postural Hypotension

Question 32

TRAMADOL | C/I

Answer 32

``` Pregnancy and Lactation Children/Elderly Liver/Renal failure Respiratory Depression Raised ICP ```