CAE, Pseudotuberculosis, Tetanus, Pregnancy Toxemia, Heartwater Flashcards
(49 cards)
This disease is manifested clinically as polysynovitis-arthritis in adult goats.
Caprine arthritis and encephalitis
Caprine arthritis and encephalitis is manifested in kids as?
leukoencephalomyelitis
Identify three clinical conditions that attribute to CAEV infection.
Subclinical or clinical interstitial pneumonia
Indurative mastitis (“hard udder)
Chronic wasting
True or False. Most CAEV infections are subclinical.
True.
CAEV belongs to which genus and family of viruses?
Lentivirus, Family Retroviridae
The primary mode of spread of CAEV is via?
Ingestion of virus-infected colostrum or milk by kids
Polysynovitis-arthritis is common in adult goats but can occur in kids aged?
6 months old
Most frequently involved body part of a goat with CAEV infection
Carpal joints
CAE in kids is generally seen in kids aged _______
2–6 months
Kids infected with Encephalomyelitis exhibit these signs (3)
Weakness, ataxia, and hind limb proprioceptive deficits
In adult goats with serologic evidence of CAEV infection, chronic interstitial pneumonia may lead to?
Progressive dyspnea
Characterized by a firm, swollen mammary gland and agalactia at the time of parturition
“hard udder” syndrome
A six-month-old dairy goat kid presents with acute onset weakness, hind limb ataxia, and subtle proprioceptive deficits, which rapidly progresses. Concurrently, several adult goats in the herd exhibit chronic, progressive carpal joint swelling. Based solely on these clinical manifestations, which of the following is the most likely underlying etiology?
Caprine Arthritis and Encephalitis Virus (CAEV) infection
The pathogenesis of CAE involves virus-infected macrophages from colostrum/milk being absorbed through the gastrointestinal mucosa. How is the infection subsequently spread throughout the host body?
Through infected mononuclear cells.
Persistence of CAEV in the host is facilitated by which specific viral characteristic?
Its capacity to become sequestered as provirus in host cells.
A key feature of the immune response to CAEV is that:
Both humoral and cell-mediated immune responses are induced, but neither is protective.
The “hard udder” syndrome associated with CAEV infection in does is characterized by?
A firm, swollen mammary gland and agalactia at the time of parturition, typically with unaffected milk quality.
Histopathologic lesions due to CAEV infection are generally described as?
Lymphoproliferative, with degenerative mononuclear cell infiltration
In chronic cases of CAEV-associated joint lesions, which specific pathological change is commonly observed?
Soft-tissue calcification involving joint capsules, tendon sheaths, and bursae.
Gross lesions associated with the neurological form of CAEV are most commonly located in which spinal cord segments and described as?
Cervical and lumbosacral segments; asymmetric, brownish pink, swollen areas.
In commercial herds, a recommended control measure for CAE involving segregation of seropositive and seronegative groups specifies a minimum separation distance of?
6 feet (1.8 m)
While skin wounds are the most common route of entry for C. pseudotuberculosis, mention two other alternative routes leading to pulmonary abscesses.
Aerosolization and inhalation into the respiratory tract.
Beyond joint swelling and lameness, what other general clinical signs are often noted in goats affected by polysynovitis-arthritis?
Weight loss and poor hair coats
After entering the body, C. pseudotuberculosis moves to regional lymph nodes. What is the typical incubation period culminating in the development of encapsulated abscesses?
1 to 3 months
