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Flashcards in CAMs Deck (12)
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1

Garlic

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

use: lower cholesterol, thins blood (studies show doesn't lower BP, BG or risk of cancers)

AE: GI SE, allergic reactions

-increases bleeding from gums

-ulcers or surgery--> increase bleeding with bleeding disorders

PDI: warfarin, ASA, NSAIDS, antiplatelet meds

-decreases saquinavir effectiveness (HIV med)

2

Ginseng

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses: increases health recovering from illness and stamina and sense of well being, treats ED and menopause sx

AE:HA, GI, insomina, palpitations, menstrual irregularities, BLEEDING

ginseng abuse syndrome (diarrhea, htn, nervousness, rash, insomnia)

PDI: CI prego and lactation

-interacts with: anticoagulant meds, ASA, NSAIDS, antiplatelet agents, drugs with hypoglycemic activity, hormonal agents, CNS stimulants

3

Black Cohosh

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Important: has salicylic acid and estrogenic binding effects

Uses:arthritis, PMS, menopause sx

AE: N/V, HTN, HA, weight gain

--CONTRAINDICATED w/h.o estrogen dependent tumors or endometrial ca

PDI:CI prego and lactation

-MAY cause BLEEDING or GI distress if taken with other salycylates (ASA)

4

Fish oil/omega 3 

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses: lower TG, may prevent dementia, essential for early brain development

AE: GI effects = nausea -fishy taste

PDI: NONE

5

Niacin

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses: synthesis & metabolism of carbs, FA, and proteins -lower LDL

AE: flushing, N/V, pruritis, constipation, hives, gout (increase uric acid), liver toxicity

PDI: CI preggos = birth defects

--interacts with STATINS--> don't take with red yeast rice

--interacts with ETOH, because metabolized in liver!

6

St. John's Wort

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses: mild to moderate depression (acts like SSRI = TCAs)

AE: GI sx, sedation, confusion, photosensitivity, dry mouth, urinary frequency, edema, anorgasmia

PDI: anti-depressants

-REDUCES effectivness of OCP

-meds metabolized by CYP3A4 (digoxin, simavastatin, verapamil, methadone, warfarin)

-CI prego or lactation

7

What are populations that should avoid herbal supplements?

-pregnant women

-infants and children

-elderly

-surgical patients (certain herbs can alter coagulation)

8

Red Yeast Rice

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses: promote blood circulation, act like statins, lower LDL

AE: HA, dizziness, gas, heartburn, stomachache, bloating, muscle aches (potential rhabdomyolysis like STATINS), thin blood

PDI: CI in pregos and lactating

-toxic to liver--> like STATINS

9

Echinacea

Why do people take it, what are the adverse effects(AE) and potential drug interactions (PDI)?

uses: to treat/prevent URI

AE: dyspepsia, diarrhea, bad taste, rashes in children

PDI: may interfere with immunosuppressant therapy doxorubicin = taken with echinacea increases proliferation of cervical and breast cancer!!! DONT take longer than 8 weeks

10

Ginko Biloba

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses:depression, vertigo, PVD and macular degeneration, improves cognitive function with alzheimers and vascular dementia

AE:GI upset, HA, increased bleeding and bruising

PDI:Increased risk of bleeding!!

do not use with: heparin, NSAIDS, warfarin or herbs (garlic, ginseng, ginger)

11

Hawthorne Berry

Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses: treat CHF

AE: nausea, sedation, arrhythmias, hypotension

PDI: anti-hypertensives, beta blockers and calcium channel blockers

-any med that causes drowziness (benzodiazepines, antiphsycotics and antihistamines) -digoxin -narcotics

12

Saw Palmetto Why do people take it, what are adverse drug effects (AE) and potential drug interactions (PDI)?

Uses: men think it works for prostate CA AE: HA, nausea, dizziness, HTN and ED PDI: prego and lactation -can interfere with OCP -RISK of bleeding with anti platelet drugs or anticoagulants