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Flashcards in Cancer Deck (19)
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1

Breaks strands of DNA

Alkylating agents

2

Cyclophosphamide
Melphalan
Chlorambucil
Lomustine

Alkylating agents

3

Interfers with topoisomerase

Anti-tumor abx

4

Anthracycline (Doxoubicin)
Epirubicin

Anti-tumor abx

5

Inhibits mitosis

Mitotic inhibitors

6

Vincristine
Vinblastine
Paclitaxel

Mitotic inhibitors
First 2 are plant alkaloids
Last inhibits disassembly of DNA

7

Cross linked DNA

Platinum drugs

8

Carboplatin

Platinum drug

9

Incorporates into DNA during transcription and translation specifically works on S-phase

Anti-metabolites

10

Methotrexate
Cystosine
5-flurouricil
6-mercaptopurine

Anti-metabolites

11

Inhibits cell signaling for cell proliferation

Tyrosine Kinase Inhibitors

12

Toceranib
Mastitinib

TKIs

13

What drug would you use to treat TVT?

Vincristine

Rapidly dividing tumor

14

What drug would you use to treat leukemia?

Hydroxyurea

15

What drug would you use to treat osteosarcs?

Carboplatin

16

What drug would you use to treat non-osteo sarcomas?

Doxorubicin

17

What is the COP protocol and what is the benefit of it?


Cyclophosphamide
Vincristine
Pred

Designed to have lower toxicity and fewer side effects

18

What is the COP protocol for?

Cancer with poor survival=palliative tx

19

What is the CHOP protocol?

Cyclophosphamide
Doxorubicin
Vincristine
Pred

High toxicity and severe side effects