Cancer Flashcards
(22 cards)
What is an oncogene
cancer causing gene
are solid tumors blood cell or non blood cell
non blood cell
what are the 2 types of solid tumors
carcinoma and sarcoma
what are the 2 types of blood cell cancer
Leukemia and Lymphoma
what is the other way to classify cancer
spontaneous or virus-associated
which is more common: spontaneous or virus-associated
spontaneous
how do you get a spontaneous CA
exposure over time
what is virus-associated CA
Infxn linked to CA
accelerate the progression of CA
what are 5 examples of DNA and RNA tumor viruses
- HPV (an sti)
- Hep B (liver CA)
- EBV (burkitts lymphoma)
- HHV (kaposis sarcoma)
- HTLV (leukemia)
what causes spontaneous CA
chemicals, radiation, diet, metabolism
can you recover and decrease your risk of Lung CA if you stop smoking
yes
is CA usually inherited
no
is CA from a single even or multiple events
multiple | progression
what are some characteristics of CA
- proliferate and invade tissue
- mets to other areas
- evade apoptosis
- turns on/off genes
is CA rare of common at the cellular level
RARE
does CA respond to inhibitory factors
NO
what are the properties of CA cells
- loss of cell signaling and cell cycle
- anchorage independent growth
- grow in the absense of stim growth signals
- seem immortal
what does Tumor suppressor genes do
encode proteins that restrain cell growth (puts the brake on cell cycle)
what does oncogenes do
encode proteins that promote loss of growth control and the conversion of a cell to the malignant state
does TSG act dominantly or recessively
recessively
does oncogenes act recessively or dominantly
dominatly
what does Proto-oncogenes do
encode proteins that have various functions in the cells normal activities
