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Flashcards in Cancer Quiz Questions Deck (20)
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1

T/F Cancer is a disorder of altered cell differentiation and growth.

True

2

T/F Surgery, radiation, and chemotherapy are the only identified treatment modalities for cancer.

False- also includes hormonal therapy and biotherapy

3

T/F The Papanicolaou test is a cytologic method used to detect cancer cells.

True

4

T/F Cell differentiation is the process whereby proliferating cells are transformed into different and more specialized cell types.

True

5

T/F Benign neoplasms are less differentiated tumors that grow in a crab-like manner to invade surrounding tissues, have cells that break loose and travel to distant sites to form metastases, and inevitably cause suffering and death unless their growth can be controlled through treatment.

False- Malignant Neoplams

6

T/F DNA synthesis takes place during the G0 phase of the cell cycle.

False- S phase

7

T/F The process of grading a tumor involves the microscopic examination of cancer cells to determine their level of differentiation and the number of mitoses.

True

8

T/F In general, benign tumors usually are named by adding the suffix “—oma” to the parenchymal tissue type from which the growth originated.

True

9

T/F The term invasion is used to describe the development of a secondary tumor in a location distant from the primary tumor.

False- Metastasis

10

T/F Hematogenic spread would involve metastasis that occurs by way of the blood vessels.

True

11

Which of the following test is MOST LIKELY considered diagnostic for colon cancer?
-colonoscopy
-FOBT
-CEA
-biopsy

colonoscopy??

12

The pathology report indicated no involvement of the lymph nodes. Thus, it is likely that treatment would include chemotherapy after surgical removal of the tumor, since metastasis has likely already occured. T/F

False

13

The mutation associated with retinoblastoma is expressed in which of the following proteins?
-p53
-pRB
-BRCA1
-DCC

pRB

14

For retinoblastoma, a germline mutation would most likely give rise to bilateral involvement before about 2 years of age. T/F

False-- 5 years old

15

Which of the following exposures provide an increased risk of lung cancer?
-Cigarette smoking
-Second-hand smoking
-Pollution
-all of the above

???All of the above

16

Lung cancer is a classic example of the initiation-promotion-progression theory of carcinogenesis. According to this theory, which of teh following statements is correct?
-Iniiation is a reversible step caused by exposure to ciarette smoke
=Promotion is initially reversible, but if it occurs after initiation tumors may form
-Progression is an irreversible step that involves the mutation of DNA within the cell
-Promotion is associated with metastasis and chromosomal instability among other cellular changes

B????

17

Oat cell carcinoma is a type of lung cancer that may be associated with SIADH since these tumor cells may release ADH. T/F

True

18

Chronic myeloid leukemia (CML) may be associated with which of the following genetic changes?
- a point mutation in a tyrosine kinase
- a translocation between two chromosomes
-the loss of a whole chromosome
-the inversion of one complete arm of chromosome

B???

19

which of the following tests can be used to detect the genetic change associated with CML?
-Karyotype
-Fluorescence in situ hybridization (FISH)
-Polymerase chain reaction (PCR)
- All of the above

??? D?

20

The result of the genetic change associated with CML is activation of a tyrosine kinase

True