Cancer Stuff Flashcards Preview

Pathology > Cancer Stuff > Flashcards

Flashcards in Cancer Stuff Deck (55):
0

Proto-oncogene: abl

CML

2

Proto-oncogene: c-myc

Burkitt's lymphoma

3

Proto-oncogene: bcl-2

Follicular and undifferentiated lyphomas

4

Proto-oncogene: erb-B2

Breast, ovarian and gastric carcinomas

5

Proto-oncogene: ras

Colon Carcinoma

6

Proto-oncogene: L-myc

Lung Cancer

7

Proto-oncogene: N-myc

Neuroblastoma

8

Proto-oncogene: ret

MEN types II and III

9

Proto-oncogene: c-kit

Gastrointestinal stromal tumor (GIST)`

10

Tumor Suppressor Gene: Rb

Retinoblastoma, osteosarcoma

11

Tumor Suppressor Gene: BRCA 1 and BRCA 2

Breast and ovarian cancers

12

Tumor Suppressor Gene:p53

Most human cancers, Li-Fraumeni syndrome

13

Tumor Suppressor Gene: p16

Melanoma

14

Tumor Suppressor Gene: APC

Colorectal Cancer (associated with FAP)

15

Tumor Suppressor Gene:WT1

Wilm's tumor

16

Tumor Suppressor Gene: NF1

Neurofibromatosis type 1

17

Tumor Suppressor Gene: NF2

Neurofibromatosis type 2

18

Tumor Suppressor Gene: DPC

Pancreatic Cancer

19

Tumor Suppressor Gene: DCC

Colon Cancer

20

CA associated with: Down Syndrome

ALL, AML

21

CA associated with: Xeroderma pigmentosum, albinism

melanoma, basal Cell CA, squamous cell CA of the skin

22

CA associated with: Chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants

Gastric AdenoCA

23

CA associated with: Tuberous Sclerosis

Astrocytoma, angiomyolipoma, cardiac rhabdomyoma

24

CA associated with: Actinic keratosis

Squamous cell CA of the skin

25

CA associated with: Barrett esophagus

Esophageal AdenoCA

26

CA associated with: Plummer-Vinson Syndrome

Squamous Cell CA of the esophagus

27

CA associated with: Cirrhosis

hepatocellular CA

28

CA associated with: Ulcerative colitis

colonic adenoCA

29

CA associated with: paget's disease of the bone

secondary osteosarcoma and fibrosarcoma

30

CA associated with: Immunodeficiency states

malignant lymphoma

31

CA associated with: AIDS

aggressive malignant lymphomas (non Hodgkins)

32

CA associated with: autoimmune diseases

lymphoma

33

CA associated with: acanthosis nigricans

visceral malignancy

34

CA associated with: dysplastic nevus

malignant melanoma

35

CA associated with: radiation exposure

sarcoma, papillary thyroid CA

36

CA associated with: aflatoxin

hepatocellular CA

37

CA associated with: vinyl chloride

liver angiosarcoma

38

CA associated with: CCl4

centrilobular necrosis, fatty liver

39

CA associated with: nitrosamines

esophagus, stomch

40

CA associated with: cigarette smoker

larynx, lung, kidney, bladde

41

CA associated with: asbestos

lung (mesothelioma and bronchogenic CA)

42

CA associated with: arsenic

Skin (SCCA) and liver (angiosarcoma)

43

CA associated with: Naphthalene dyes

bladder (transitional cell CA)

44

CA associated with: Alkylating agents

Leukemia

45

Tumor marker: PSA

prostate cancer

46

Tumor marker: Prostatic acid phosphatas

prostate cancer

47

Tumor marker: CEA

colorectal and pancreatic cancer, Gastric CA, breast CA

48

Tumor marker: AFP

hepatocellular CA, nonseminomatous GCTs

49

Tumor marker: b-HCG

hydatidiform mole, choriocarcinoma, gestational trophoblastic tumor

50

Tumor marker: CA-125

ovarian, malignant epithelial tumors

51

Tumor marker: S-100

melanoma, neural tumors, astrocytomas

52

Tumor marker: Alkaline phosphatase

metastases tot he bone, obstructive biliary disease, paget's disease of the bone

53

Tumor marker: bombesin

neutroblastoma, lung and gastric CA

54

Tumor marker: TRAP

hairy cell leukemia (B-cell neoplasm)

55

Tumor marker: CA-19-9

Pancreatic Adenocarcinoma