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Cancer Stuff Flashcards

(55 cards)

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1
Q

Proto-oncogene: abl

A

CML

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2
Q

Proto-oncogene: c-myc

A

Burkitt’s lymphoma

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3
Q

Proto-oncogene: bcl-2

A

Follicular and undifferentiated lyphomas

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4
Q

Proto-oncogene: erb-B2

A

Breast, ovarian and gastric carcinomas

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5
Q

Proto-oncogene: ras

A

Colon Carcinoma

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6
Q

Proto-oncogene: L-myc

A

Lung Cancer

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7
Q

Proto-oncogene: N-myc

A

Neuroblastoma

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8
Q

Proto-oncogene: ret

A

MEN types II and III

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9
Q

Proto-oncogene: c-kit

A

Gastrointestinal stromal tumor (GIST)`

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10
Q

Tumor Suppressor Gene: Rb

A

Retinoblastoma, osteosarcoma

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11
Q

Tumor Suppressor Gene: BRCA 1 and BRCA 2

A

Breast and ovarian cancers

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12
Q

Tumor Suppressor Gene:p53

A

Most human cancers, Li-Fraumeni syndrome

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13
Q

Tumor Suppressor Gene: p16

A

Melanoma

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14
Q

Tumor Suppressor Gene: APC

A

Colorectal Cancer (associated with FAP)

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15
Q

Tumor Suppressor Gene:WT1

A

Wilm’s tumor

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16
Q

Tumor Suppressor Gene: NF1

A

Neurofibromatosis type 1

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17
Q

Tumor Suppressor Gene: NF2

A

Neurofibromatosis type 2

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18
Q

Tumor Suppressor Gene: DPC

A

Pancreatic Cancer

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19
Q

Tumor Suppressor Gene: DCC

A

Colon Cancer

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20
Q

CA associated with: Down Syndrome

A

ALL, AML

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21
Q

CA associated with: Xeroderma pigmentosum, albinism

A

melanoma, basal Cell CA, squamous cell CA of the skin

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22
Q

CA associated with: Chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants

A

Gastric AdenoCA

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23
Q

CA associated with: Tuberous Sclerosis

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A

Astrocytoma, angiomyolipoma, cardiac rhabdomyoma

24
Q

CA associated with: Actinic keratosis

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A

Squamous cell CA of the skin

25
CA associated with: Barrett esophagus
Esophageal AdenoCA
26
CA associated with: Plummer-Vinson Syndrome
Squamous Cell CA of the esophagus
27
CA associated with: Cirrhosis
hepatocellular CA
28
CA associated with: Ulcerative colitis
colonic adenoCA
29
CA associated with: paget's disease of the bone
secondary osteosarcoma and fibrosarcoma
30
CA associated with: Immunodeficiency states
malignant lymphoma
31
CA associated with: AIDS
aggressive malignant lymphomas (non Hodgkins)
32
CA associated with: autoimmune diseases
lymphoma
33
CA associated with: acanthosis nigricans
visceral malignancy
34
CA associated with: dysplastic nevus
malignant melanoma
35
CA associated with: radiation exposure
sarcoma, papillary thyroid CA
36
CA associated with: aflatoxin
hepatocellular CA
37
CA associated with: vinyl chloride
liver angiosarcoma
38
CA associated with: CCl4
centrilobular necrosis, fatty liver
39
CA associated with: nitrosamines
esophagus, stomch
40
CA associated with: cigarette smoker
larynx, lung, kidney, bladde
41
CA associated with: asbestos
lung (mesothelioma and bronchogenic CA)
42
CA associated with: arsenic
Skin (SCCA) and liver (angiosarcoma)
43
CA associated with: Naphthalene dyes
bladder (transitional cell CA)
44
CA associated with: Alkylating agents
Leukemia
45
Tumor marker: PSA
prostate cancer
46
Tumor marker: Prostatic acid phosphatas
prostate cancer
47
Tumor marker: CEA
colorectal and pancreatic cancer, Gastric CA, breast CA
48
Tumor marker: AFP
hepatocellular CA, nonseminomatous GCTs
49
Tumor marker: b-HCG
hydatidiform mole, choriocarcinoma, gestational trophoblastic tumor
50
Tumor marker: CA-125
ovarian, malignant epithelial tumors
51
Tumor marker: S-100
melanoma, neural tumors, astrocytomas
52
Tumor marker: Alkaline phosphatase
metastases tot he bone, obstructive biliary disease, paget's disease of the bone
53
Tumor marker: bombesin
neutroblastoma, lung and gastric CA
54
Tumor marker: TRAP
hairy cell leukemia (B-cell neoplasm)
55
Tumor marker: CA-19-9
Pancreatic Adenocarcinoma

Pathology (25 decks)

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