Canine Alopecia- nonpruritic, non-inflammatory Flashcards

(29 cards)

1
Q

the absence of hair, focal or generalized

A

alopecia

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2
Q

Allergies wont cause alopecia unless

A

1) Secondary bacterial infection
2) Traumatic - scratching out hairs

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3
Q

How can you make sure alopecia is traumatic

A

trichogram - see if the remnants of the hairs are sheered off

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4
Q

What is most common cause of hyperpigmentation

A

Inflammation

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5
Q

What are differentials for nonpruritic, noninflammatory alopecia

A

1) Hypothyroidism
2) Hyperadrenocorticism
3) Sex hormone dermatosis
4) Flank alopecia
5) Post-clipping alopecia
6) Color dilution alopecia
7) Teelogen effluvium
8) Pattern baldness

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6
Q

Hormonal alopecia presents as ____ ***

A

truncal hair loss sparing the head and distal extremities

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7
Q

What is resting phase of hair

A

telogen

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8
Q

What is growing phase of hair

A

Anagen

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9
Q

How might you treat follicular dysplasia (flank alopecia)

A

Melatonin - about 50-50 give about 5mg Nature’s Bounty Melatonin

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10
Q

How might you treat post-clipping alopecia

A

Melatonin - about 50-50 give about 5mg Nature’s Bounty Melatonin

gets the hair out of the telagen phase

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11
Q

What causes color dilution alopecia

A

genetics - ex: Dobermans

selected to dilute hair coat color but melanin is clumped in the keratin. Not enough keratin to support hair and it breaks, thus causing alopecia

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12
Q

How might you treat color dilution alopecia

A

No treatment

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13
Q

How do you cure pattern baldness

A

No cure

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14
Q

What breeds get Alopecia X

A

wooly breeds
-Chow Chow
-Samoyed
-Keeshond
-Husky
-Malamute
-Norweigan elkhound
-American Eskimo

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15
Q

T/F: dogs with Alopecia X are systemically normal

A

true

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16
Q

What causes Alopecia X

A

appears to be a follicular signaling problem, likely associated with adrenal hormones and stuff

-response to hormone stimulators/inhibitors
-hair transplants (mice) restore growth

17
Q

How do you diagnose Alopecia X

A

Biopsy - flame follicles
catagen hairs with tricholemmal keratin at follicular base

might need to do Sex Hormone assay? (Tennessee)

18
Q

How might you treat Alopecia X

A

1) Benign neglect (cosmetic)
2) Neutering (males)
3) Melatonin (40%) - 3-9mg PO BID or SQ implant (Dermatonin)
4) Trilostane (85%)- requires monitoring, dont really do
5) Deslorelin (GnRH agonist)-implant - works in intact males
6) Microneedling? for intact males
7) Phovia light therapy

19
Q

another word for dandruff

20
Q

What causes sebaceous adenitis

A

immune mediated disease (idiopathic) that targets sebaceous glands

no sebaceous glands = dry skin

21
Q

What breeds typically get sebaceous adenitis

A

Standard poodle, Samoyed, Akita

22
Q

When doing a trichogram, what will the hair look like in a dog with sebaceous adenitis

A

follicular casting

23
Q

What is a hallmark of sebaceous adenitis

A

Severe hypotrichosis with adherent scale
Follicular casting

Pruritus if concurrent allergy/infection

24
Q

How do you diagnose sebaceous adenitis

A

Biopsy - see no sebaceous glands
sometimes pyogranulomatous variant
nodular form (less common)

need OFA breed registry for SA

25
T/F: sebaceous adenitis is not itchy
True- but often itchy because of concurrent allergy/ infection
26
How do you treat sebaceous adenitis
Option 1: Topical therapy - mineral oil at least once a week. cumbersome to do but cheap Option 2: Systemic Therapy ie Cyclosporine both together work the best lifetime treatment Adjuncts: Douxo Seborrhea spray/shampoo
27
What is topical therapy for sebaceous adenitis
Alpha keri bath oil (mineral/lanolin, PEG-4) 30 minutes to apply, soak (at least) 30 minutes to rinse off (Dawn) Weekly Worse before better remove fake hair Cheap but time consuming
28
What is systemic therapy for sebaceous adenitis
Oral cyclosporine 5mgkg/day takes 4-6 weeks for full effect watch out for vomiting/diarrhea gingival hyperplasia taper to effect expensive
29
What is most effective treatment for sebaceous adentitis
Combination cyclosporine/topical oil therapy likely most effective; adequate response to therapy may be 3-4 months