Cannabidiol (CBD)

Question 1

What does CBD stand for?

Answer 1

Cannabidiol

Question 2

What is the boiling point/vaporization temperature of CBD?

Answer 2

356° F (180° C)

Question 3

What is the boiling point / vaporization temperature of CBDA?

Answer 3

248° F (120° C)

Question 4

What is the percentage of CBDA found in most commercial cannabis?

Answer 4

Between 0% - 4%
Some strains can have as much as 30% CBDA

Question 5

CBD has similar health benefits to THC, however it doesn’t have certain side effects found with THC. What are the negative side effects not found with CBD?

Answer 5

Unlike THC, CBD does not cause psychoactivity, drowsiness, increased appetite, increased anxiety, nor increased heart rate.

Question 6

why doesn’t CBD negatively affect the user in the way that THC does?

Answer 6

Because CBD works as a CB receptor Agonist.

Question 7

What is the binding affinity of CBD to the CB1 and CB2 receptors?

Answer 7

CBD has a very low binding affinity with the receptors CB1 and CB2, Because it acts as a Agonist and essentially blocks them so that other cannabinoids cannot bind with them. This makes CBD helpful in counteracting the negative effects of other cannabinoids such as THC.

Question 8

CBD affects the body differently from the other cannabinoids, in what ways does CBD change the body?

Answer 8

CBD affects the body differently from other cannabinoids by changing the body’s response to stress. It turns off signals that cause the body to stop producing endocannabinoids and inhibits the reuptake of endocannabinoids, allowing for efficient production in the endocannabinoid system. This reduces the body’s stress response and can help alleviate symptoms of anxiety and depression. Additionally, CBD blocks alpha-adrenergic receptors, reducing blood pressure in stressful situations. It also reduces dopamine signaling in the brain, which can help alleviate symptoms of certain mental disorders. Finally, CBD directly heals the gut by producing Claudin 1, which helps heal the gut lining. These effects make CBD a unique and valuable cannabinoid for treating a variety of conditions related to stress and inflammation.

Question 9

CBD and CBDA are especially effective for what conditions? (5)

Answer 9

Epilepsy
Rheumatoid arthritis
Diabetes
Weight loss
Anxiety

Question 10

What is the CBD to THC ratio for Charlotte’s Web strain and what value does the strain have?

Answer 10

The CBD:THC ratio for Charlotte’s Web is 24:1 and was developed to treat a rare form of epilepsy.

Question 11

What is the relationship between CBD and rheumatoid arthritis?

Answer 11

CBD is the only cannabinoid with positive scientific evidence of improving rheumatoid arthritis due to its immunosuppressive effects that alleviate the chronic inflammation caused by the autoimmune disorder.

Question 12

What are the advantages of using CBD to treat type 2 diabetes as opposed to THC?

Answer 12

CBD is preferred over THC for treating type 2 diabetes as THC causes psychoactive effects, while CBD improves inflammation, glucose metabolism, and insulin sensitivity, which are important factors in treating this condition.

Question 13

What does CBD have to do with weight loss?

Answer 13

CBD is an appetite suppressant and reduces fat cells.

Question 14

How does CBD help with anxiety caused by THC?

Answer 14

CBD Counteracts the paranoia sometimes brought on by THC Because it acts as an Agonist which prevent THC from connecting to the CB1 and CB2 receptors by blocking them.

Question 15

How does CBD help heal the gut?

Answer 15

CBD helps produce Claudin-1 which helps maintain the integrity and function of the tight junctions in the gut.

Question 16

What are two reasons to avoid strains with high CBD?

Answer 16

One reason to avoid CBD is if you have wasting syndrome or an eating disorder since CBD is an appetite suppressant and reduces fat cells.
Another reason to avoid CBD is if you are undergoing chemotherapy treatment since CBD affects the way your body metabolizes chemotherapy drugs. Talking to your doctor is often recommended before using CBD as a medicine.

Question 17

What receptors does CBD activate and how does this affect the body?

Answer 17

CBD affects the body by activating 5-HT1A receptors, which helps regulate mood and stress, and release dopamine in the prefrontal cortex to aid in schizophrenia. It also activates TRPV1 receptors to help regulate pain from inflammation. Additionally, CBD inhibits the breakdown of an endocannabinoid called AEA by the enzyme FAAH, leading to more benefits from AEA. Finally, CBD inhibits the activity of cytochrome P450 enzymes, which metabolize many drugs and can result in increased drug concentration if not considered when taking CBD.

Question 18

Which transmitters does CBD inhibit from reuptake? (5)

Answer 18

Noradrenaline
Dopamine
Serotonin
GABA
AEA

Question 19

One of the ways in which CBD Impacts the body is that it inhibits certain enzymes associated with the liver. What about this should be considered by patients when combining CBD with other medications?

Answer 19

CBD inhibits cytochrome p450 enzymes in the liver, which reduces the metabolization of many drugs, including THC. This effect should be considered when taking other medications, as failure to do so may increase their concentration in the bloodstream.

Question 20

Does CBD affect the mental state of the user?

Answer 20

Yes, it reduces anxiety, and is non intoxicating.

Question 21

Does CBD affect the nervous system of the user?

Answer 21

Yes
Relieves pain and relaxes muscles
Protects nervous system
Promotes brain cell growth (Multiple sclerosis)
Anti-epileptic (At high doses, especially when paired with low doses of THC)
Degrades the plaque that contributes to Alzheimer’s disease

Question 22

The CBD affect inflammation in the user?

Answer 22

Yes
Excellent anti-inflammatory
Relieves rheumatoid arthritis at high doses
Treats autoimmune disorders

Question 23

Does CBD affect cancer in the user?

Answer 23

Yes, CBD inhibits cancer cell growth and is an antioxidant

Question 24

Does CBD affect the digestive system of the user?

Answer 24

Yes, CBD suppresses appetite, is anti-diabetic (lowers blood sugar), relieves IBS and other gastrointestinal disorders, and reduces nausea.

Question 25

Does CBD affect the circulatory system in the user?

Answer 25

Yes CBD improves circulation in the user.

Question 26

Does CBD affect the skin of the user?

Answer 26

Yes, CBD relieves psoriasis, is an anti-acne, and crosses transdermal barrier 10 times better than THC.

Question 27

The CBD affect the skeletal system of the user?

Answer 27

Yes, CBD stimulates bone growth

Question 28

The CBD affect the eyes of the user?

Answer 28

No, CBD has shown no known effect on the user’s eyes.

Question 29

Does CBD affect the respiratory system of the user?

Answer 29

No, no known effect has been shown to affect the user’s respiratory system.

Question 30

Does CBD affect infection within the user?

Answer 30

Yes, CBD has some antibiotic properties, especially CBDA.