Cannabis

Question 1

Which act prohibited cannabis?

Answer 1

Controlled Substances Act of 1970

Question 2

Cannabinoids are ___ of cannabinoid receptors

a. agonists
b. antagonists

Answer 2

a. agonists

• dronabinol (Marinol) CIII
• nabilone (Cesamet) schedule II
• nabiximols not approved in US

Question 3

What class is marijuana?

Answer 3

C-I

Question 4

Hemp may be grown legally as long as it has less than __ % THC

Answer 4

0.3

Agricultural Improvement Act of 2018

Question 5

Federal Rules:

CBD oil derived from marijuana is considered illegal

a. true
b. false

Answer 5

a. true

CBD oil derived from hemp is legal

hemp removed from controlled substance

Question 6

___ is a hemp extract with all the cannabinoids except for THC, with means it has all the beneficial properties of cannabis without the high

Answer 6

GENESIS II

Question 7

Texas rules:

Qualified physicians may prescribe low THC cannabis to a pt with ___

Answer 7

intractable epilepsy

seizure disorder in which the pt’s seizures have been treated by two or more appropriately chosen and maximally titrated antiepileptic drugs that have failed to control the seizures

Question 8

Texas rules:

Low-THC cannabis has up to __% THC, and at least __% cannabidiol (CBD)

Answer 8

0.5, 10

Question 9

Colorado rules:

At what age can a pt use marijuana for medical use?

Answer 9

any age

need marijuana registry ID card

Question 10

Colorado rules:

At what age can someone use marijuana for recreational use?

Answer 10

21 or over

Board of Pharmacy rules set the limits

Question 11

Medical use is __

a. risk vs risk
b. benefit vs risk

Answer 11

b. benefit vs risk

Question 12

Recreational use is ___

a. risk vs risk
b. benefit vs risk

Answer 12

a. risk vs risk

Question 13

Which cannabinoid receptors are in the periphery?

a. CB1
b. CB2

Answer 13

b. CB2

primarily immune related

Question 14

which cannabinoid receptors are in the nervous system, connective tissues, gonads, glands, and other organs?

a. CB1
b. CB2

Answer 14

a. CB1

Question 15

Two endocannabinoids that the body naturally produces?

Answer 15

anandamide

2-arachidonoylglycerol

Question 16

___ = oral THC

Answer 16

dronabinol

Question 17

What cannabinoid is FDA approved for cachexia in AIDS, CINV, and postoperative n/v?

Answer 17

dronabinol

schedule III

may improve cancer related pain at higher doses

Question 18

___ is only FDA approved for CINV

a. dronabinol
b. nabilone
c. nabiximols

Answer 18

b. nabilone

Question 19

___ is not FDA approved

a. dronabinol
b. nabilone
c. nabiximols

Answer 19

c. nabiximols

Question 20

The majority of supportive data for cannabis and pain relief is for what type of pain?

Answer 20

neuropathic

Question 21

___ are the plant component responsible for flavors and fragrances of cannabis

Answer 21

terpenes

Question 22

3 species of cannabis?

Answer 22

sativa
indica
ruderalis

Question 23

Licensed pharmacist must be on site where marijuana is being sold or dispensed in which state?

a. Connecticut
b New York
c. Minnesota

Answer 23

b. New York

Question 24

Dispensaries must be owned and operated by pharmacists in which state?

a. Connecticut
b New York
c. Minnesota

Answer 24

a. Connecticut

Question 25

Law allows up to 8 dispensaries in which state? a. Connecticut b New York c. Minnesota

Answer 25

c. Minnesota 3 are currently running and pharmacists dispense in one

Question 26

CBD crystals are legal because they contain no THC. a. true b. false

Answer 26

b. false DEA statement: “At present, this material (CBD oil) is being illegally produced and marketed in the United States in violation of two federal laws:  The Controlled Substances Act (CSA) and the Federal Food, Drug, and Cosmetic Act (FDCA).” This would apply to CBD crystals also…

Question 27

Why is GI use dangerous?

Answer 27

peak concentration is in 1-3 hours pts do not feel effect and re-dose

Question 28

CBD inhibits which 3 CYPs?

Answer 28

2C19 3A4 2D6

Question 29

Cannabis is associated with __ syndrome

Answer 29

amotivational

Question 30

There is evidence that the same carcinogens in tobacco smoke are present in marijuana smoke. a. true b. false

Answer 30

a. true

Question 31

Takes at least __ hours to resolve impairment from smoking and at least __ hours from oral ingestion

Answer 31

6, 8

Question 32

What syndrome results from chronic, heavy use of marijuana?

Answer 32

cannabinoid hyperemesis syndrome Sx are relieved by hot shower

Question 33

Cannabinoid hyperemesis syndrome is associated with what receptor?

Answer 33

transient receptor potential vanilloid 1 (TRPV1)

Question 34

What is applied to abdomen, arms, and/or back to treat cannabinoid hyperemesis syndrome?

Answer 34

capsaicin 0.025-0.075%

Question 35

The synthetic cannabinoid K2 aka spice is a C-I a. true b. false

Answer 35

a. true

Question 36

Use what class of meds to treat synthetic cannabinoid toxicity?

Answer 36

benzos if agitation/psychosis persists consider antipsychotics (haloperidol)

Question 37

Synthetic cannabinoid Toxicity: Rhabdomyolysis is possible so specific focus on __ and ___ monitoring

Answer 37

SCr, potassium electrolyte monitoring also perform electrocardiogram