Carbohydrates

Question 1

A pancreatic beta cell tumor which might be present in hypoglycemia

Answer 1

Insulinoma

Question 2

It is the most common glycogen storage disease

Answer 2

Glucose-6-phosphatase deficiency type 1, also “ von Gierke disease’

Question 3

Symptoms/manifestations of von Gierke disease

Answer 3

Hypoglycemia, hyperlipidemia, uricemia, and growth retardation

Question 4

A congenital deficiency of one of three enzymes involved in galactose metabolism, resulting in increased levels of galactose in plasma.

Answer 4

Galactosemia

Question 5

The enzyme affected in Galactosemia

Answer 5

Galactose-1- phosphate uridyltransferase

Question 6

Method of measurement for glucose

Answer 6

Serum/plasma/whole blood

Question 7

How is specimen for glucose measurement stored

Answer 7

Refrigerated and centrifuged within 1 hour

Question 8

Tubes used in glucose measurement

Answer 8

Sodium fluoride (gray-top)

Question 9

Diurnal variation for FBG

Answer 9

Higher in the morning

Question 10

The most specific enzyme reacting with only B-D-glucose

Answer 10

Glucose oxidase

Question 11

Glucose oxidase converts B-D-glucosr to what

Answer 11

Gluconic acid

Question 12

It represents glycosylated albumin

Answer 12

Fructosamine

Question 13

Used to assess glycemic control over the past 2-3 weeks in cases when HbA1C is unreliable

Answer 13

Fructosamine (glycosylated albumin)