Carbohydrates Flashcards
Carbohydrate Diseases (37 cards)
These are hydrates of aldehyde or ketone derivates based on the location of the CO functional
group.
Carbohydrates
It is both an endocrine and exocrine organ in the control of carbohydrate metabolism.
Pancreas
it secretes the hormones insulin, glucagon, and somatostatin from different cells residing in the islets of Langerhans in the pancreas
Endocrine gland
it produces and secretes an amylase responsible for the breakdown of ingested complex
carbohydrates
Exocrine Gland
- primary hormone responsible for entry of glucose into the cell
- beta cells
- released when the glucose levels are high
- stored from sources such as liver, fat, and muscle
insulin
- primary hormone responsible for increasing glucose - hyperglycemic agent
- alpha cells
- released during stress and fasting states
glucagon
- secreted by the cells of the zona fasciculata and zona reticularis of the adrenal cortex
- decrease intestinal entry of glucose into the cell
Cortisol and corticosteroids (Glucocorticoids)
These are released from the chromaffin cells of the adrenal medulla
- They inhibit insulin secretion and promotes glycogenolysis and lipolysis
Catecholamines
- secreted by the anterior pituitary gland
- decrease entry of glucose into the cell
Growth Hormone (Somatotropin) aka GH
promotes glycogenolysis, gluconeogenesis and intestinal absorption of glucose
Thyroid hormones
stimulates release of cortisol from the adrenal cortex
Adrenocorticotropic hormone (ACTH)
produced by the delta cells of the islets of langerhans and inhibits the action of insulin
Somatostatin
increase in blood glucose concentration
- toxic to beta cell function and impairs insulin secretion
Hyperglycemia
an imbalance between glucose utilization and production
- decreased glucose levels and can have many causes
hypoglycemia
a group of metabolic disorders characterized by hyperglycemia resulting from defects in insulin secretion, insulin receptors or both
diabetes mellitus
- described as the Type 1a or 1.5 DM
-also referred to as the slow immune-mediated DM or the slowly progressive insulin-dependent type 1 diabetes mellitus (SPIDD)
Latent Autoimmune Diabetes of Adulthood (LADA)
- idiopathic type 1 DM or type 1b.
- strongly inherited and associated with the absence of B-cell autoantibodies.
Fulminant Type Diabetes (FT1D)
- due to impaired ability to metabolize carbohydrates usually caused by a deficiency of insulin, metabolic or hormonal changes
- occurs during pregnancy and disappears after delivery but, in some cases, returns years later.
- type of glucose intolerance with onset or first recognition during pregnancy (diabetic women who
become pregnant are not included in this category) - through 2- hour OGTT: One-Step Method (with 75 grams
glucose load, commonly used)
Two-Step Method (50 grams initially; 100g glucose load as follow-up)
Gestational Diabetes Mellitus (GDM)
a condition that
happens when the body
has too much cortisol, a
hormone made by the
adrenal glands
Cushing’s disease
excess hair growth
hirsutism
- rare type of tumor that forms in
the adrenal glands, which are located on top of your kidneys - produce too much of adrenaline and noradrenaline
Pheocytochroma
a condition that occurs
when the body produces too
much growth hormone
acromegaly
- a condition where the thyroid
gland makes too much thyroid
hormone
hyperthyroidism
- a condition where the thyroid
gland doesn’t make enough
thyroid hormone
hypothyroidism