Cardiac amyloidosis Flashcards Preview

CV PATH...Cardiomyopathy > Cardiac amyloidosis > Flashcards

Flashcards in Cardiac amyloidosis Deck (12)
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1
Q

most commonly…

A

restrictive cardiomyopathy w/ impaired compliance

2
Q

Cause

A

deposition of amyloid in interstitium of heart

3
Q

epidemiology

A

older adults

4
Q

Senile amyloidosis

A

transthyretin deposition commonly limited to heart

familial
autosomal dominant
AA

5
Q

gross pathology

A

heart is

  • -enlarged,
  • -firm,
  • -tan,
  • -waxy
6
Q

microscopic pathology

A

interstitial deposits of hyaline smooth eosinophilic material initially perivascular

…Congo red stain!!

7
Q

complications

A

HF
heart block
arrhythmias

8
Q

symptoms

A

exercise intolerance
fatigue
dyspnea

9
Q

signs

A

JVD increased w/ inspiration (Kussmaul’s sign!)

peripheral edema
ascites
enlarged tender liver
rales

10
Q

diagnosis

A

biopsy

11
Q

treatment

A

transplantation and try to prevent recurrence

12
Q

Common presentation:

A

older adult w/ HF