Cardiac and Pacemaker AP

Question 1

what does the P wave show?

Answer 1

depolarisation of the atria

Question 2

QRS complex?

Answer 2

depolarisation of the ventricles

Question 3

T wave

Answer 3

repolarisation of the ventricles

Question 4

2 AP in the heart

Answer 4

Pacemaker AP and Cardiac AP

Question 5

which phases does the cardiac action potential have

Answer 5

0, 2 and 3

Question 6

what is phase 0 in the cardiac AP

Answer 6

fast Na+ influx via VGNa+C, causing rapid depolarisation, and rapid conduction of the AP

Question 7

what drugs target phase 0 of the Cardiac AP

Answer 7

class 1 anti-arrhythmic

Question 8

what is phase 2 of the cardiac AP

Answer 8

slow Ca influx via L-type VGCaC, balanced by K efflux via VGKC

Question 9

what determines the duration of the cardiac AP

Answer 9

the plateau

Question 10

what drugs target phase 2 of the cardiac AP

Answer 10

Class 4 anti-arrhythmic

Question 11

what is phase 3 of the cardiac AP

Answer 11

increased K efflux via VGKC, causing repolarisation and termination of the cardiac AP

Question 12

what drugs target phase 3 of the cardiac AP

Answer 12

class 3 antiarrhythmic

Question 13

what phases are in the pacemaker AP

Answer 13

0, 3 and 4

Question 14

what is phase 0 in the pacemaker AP

Answer 14

slow depolarisation via L-type VACaC

Question 15

what drugs target phase 0 in the pacemaker AP

Answer 15

Class 4

Question 16

which phase is absent in the Pacemaker AP

Answer 16

2

Question 17

what is phase 3 in the pacemaker AP

Answer 17

repolarisation of the AP, increase K+ efflux

Question 18

what is phase 4 in the pacemaker AP

Answer 18

slow depolarising pacemaker potential