Cardiac conduction system Flashcards

(27 cards)

1
Q

cardiac conduction system

A

cellular network composed of highly specialised cell populations that generate and conduct electrical activity through the heart

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2
Q

cardiac conduction system purpose

A

critical for synchronised rhythmic myocardial contraction and opening and closing of valves for efficient pumping of blood

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3
Q

cardiac conduction system cells

A

pacemaker cells and conduction fibres

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4
Q

pacemaker cells function

A

spontaneously generate electrical activity

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5
Q

pacemaker cells locations (5)

A

SAN, AVN, Purkinje fibres, atrioventricular ring, pulmonary vein sleeves

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6
Q

pacemaker cell characteristics (6)

A

smaller size, few contractile elements, many mitochondria, abundant gap junctions, ANS innervation, specialised ion channels

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7
Q

pacemaker cell ion channels (4)

A

funny sodium channels, T-type and L-type calcium channels, fewer leaky potassium channels

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8
Q

conduction fibre cells function

A

preferentially conduct electrical activity throughout heart

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9
Q

conduction fibre cell characteristics (5)

A

large size, abundant gap junctions, fewer myofibrils, rich in glycogen, specialised ion channels

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10
Q

conduction fibre ion channels (3)

A

fast sodium channels, L-type calcium channels, leaky potassium channels

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11
Q

SAN function

A

primary pacemaker of the heart

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12
Q

SAN location

A

superior vena cava junction in right atrium, 9/10 inferior to RAA crest, 1/10 extends as horseshoe across crest into inter-atrial groove

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13
Q

wandering pacemaker meaning

A

leading pacemaker sites are not fixed and can vary beat to beat

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14
Q

inferior shifts in leading pacemaker site indication

A

SAN dysfunction

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15
Q

AVN conduction axis

A

direct myocardial conduction pathway linking atrial and ventricular myocardium

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16
Q

AVN conduction axis function

A

conduction delay to allow ventricular filling

17
Q

AVN function

A

delays impulses coming from the SAN before transmitting them to the His bundle

18
Q

AVN location

A

inferior part of right atrium, near septal cusp of tricuspid valve

19
Q

compact AV node function

A

core part of AVN densely packed with cells that significantly slow conduction velocity forming critical delay

20
Q

compact AV node location

A

base of inter-atrial septum, near coronary sinus opening and septal cusp of tricuspid valve

21
Q

nodal extensions function

A

contains transitional cells that surround compact AV node, connect surrounding conduction pathways and facilitate gradual slowing of electrical impulse

22
Q

triangle of Koch location

A

triangular area of right atrial wall containing the AVN

23
Q

triangle of Koch boundaries

A

tendon of todaro, tricuspid valve annulus, coronary sinus orifice

24
Q

tendon of todaro

A

fibrous structure extending from eustachian valve of inferior vena cava toward central fibrous body (posterior boundary of triangle)

25
tricuspid valve annulus
insertion of septal cusp of tricuspid valve (anterior boundary of triangle)
26
coronary sinus orifice
opening of coronary sinus into right atrium (inferior boundary of triangle)
27
His bundle function
transmits electrical impulse from AVN to ventricles via left and right bundle branches