Cardiac conduction system Flashcards
(27 cards)
cardiac conduction system
cellular network composed of highly specialised cell populations that generate and conduct electrical activity through the heart
cardiac conduction system purpose
critical for synchronised rhythmic myocardial contraction and opening and closing of valves for efficient pumping of blood
cardiac conduction system cells
pacemaker cells and conduction fibres
pacemaker cells function
spontaneously generate electrical activity
pacemaker cells locations (5)
SAN, AVN, Purkinje fibres, atrioventricular ring, pulmonary vein sleeves
pacemaker cell characteristics (6)
smaller size, few contractile elements, many mitochondria, abundant gap junctions, ANS innervation, specialised ion channels
pacemaker cell ion channels (4)
funny sodium channels, T-type and L-type calcium channels, fewer leaky potassium channels
conduction fibre cells function
preferentially conduct electrical activity throughout heart
conduction fibre cell characteristics (5)
large size, abundant gap junctions, fewer myofibrils, rich in glycogen, specialised ion channels
conduction fibre ion channels (3)
fast sodium channels, L-type calcium channels, leaky potassium channels
SAN function
primary pacemaker of the heart
SAN location
superior vena cava junction in right atrium, 9/10 inferior to RAA crest, 1/10 extends as horseshoe across crest into inter-atrial groove
wandering pacemaker meaning
leading pacemaker sites are not fixed and can vary beat to beat
inferior shifts in leading pacemaker site indication
SAN dysfunction
AVN conduction axis
direct myocardial conduction pathway linking atrial and ventricular myocardium
AVN conduction axis function
conduction delay to allow ventricular filling
AVN function
delays impulses coming from the SAN before transmitting them to the His bundle
AVN location
inferior part of right atrium, near septal cusp of tricuspid valve
compact AV node function
core part of AVN densely packed with cells that significantly slow conduction velocity forming critical delay
compact AV node location
base of inter-atrial septum, near coronary sinus opening and septal cusp of tricuspid valve
nodal extensions function
contains transitional cells that surround compact AV node, connect surrounding conduction pathways and facilitate gradual slowing of electrical impulse
triangle of Koch location
triangular area of right atrial wall containing the AVN
triangle of Koch boundaries
tendon of todaro, tricuspid valve annulus, coronary sinus orifice
tendon of todaro
fibrous structure extending from eustachian valve of inferior vena cava toward central fibrous body (posterior boundary of triangle)