Cardiac HF/anticoag Flashcards Preview

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Flashcards in Cardiac HF/anticoag Deck (10):
1

Classifications HF

a- risk of HF
b-strucutral disease no symptoms
c- disease past or current symptoms
d- refractory, all the time

2

Treatment HF
A
B
C
D

a- acei
b-ace+beta
c- ace+beta+loop
end of c add digoxin
d- all of the above, dobutamine

3

HF
do not use

use ACE in all except

use beta if

CCB

pregnancy, bilateral renal artery stenosis, high potassium, angioedema

history MI

4

Digoxin

metabolism
excretion
need?
interactions

not extensively metabolized

excreted unchanged in kidneys

loading dose (half life long)- IV first then switch to oral

quinidine, amiodarone, CCB (verapimil, diltiazem)

5

Antiarrythmic categories

Sodium channel blockers- lengthen duration action potential, shorten duration action potential, minimally increase action potential- (quinidine, lidocaine, phenytoin, flecainide)

Beta blocker (sotalol is II and III)

Potassium channel blocker- prolong duration action potential, reduce speed of conduction (amiodarone)

Calcium channel blocker (verapamil, diltiazem)

6

Amiodarone

prolong..

Metabolism

Elimination

ADRs

Interactions

effective refractory period, reduce sped of conduction
Class III antiarrythmic

long half life- need loading dose

excreted in feces

thyroid, pulmonary fibrosis*

MANY, grapefruit juice

7

Beta blocker ISA

MI patients?
Patients experiencing bradycardia?

MI patients- without ISA post MI

Bradycardia- with ISA

8

Nitrates
ADRS

dont give to

hypotension...

interactions

pregnancy?

headache, orthostatic hypotension, tachycardia

patients with ICP

myocardial ischemia, arrythmia, rebound hypertension

use with vasodilators like viagra
additive hypotension beta blockers etc. alcohol

cat c

9

Acute angina use

stable angina use

sublingual nitroglyceride sl every 5 minutes up to 3 doses

isosorbide dinitrate

10

Peripheral vasodilators

adrs

interactions

minoxidil hydralazine

adrs: tachycardia, increase contractility, sodium and water retention, headache

nsaids