Cardiology Flashcards
(22 cards)
What does the P wave of an ECG represent?
atrial depolarisation
What does the QRS complex of an ECG represent?
ventricular depolarisation
What does the ST segment of an ECG represent?
Interval between ventricular depolarisation and repolarisation
Define systole
Contraction phase
Define diastole
Filling phase
What is normal systemic systolic and diastolic BP respectively?
120 mmHg and 80 mmHg
What is normal pulmonary systolic and diastolic BP respectively?
28 mmHg and 10 mmHg
Cardiac output (CO) =
Stroke volume (SV) x Heart rate (HR)
What is normal ejection fraction (LVEF)?
55-70% of SV
What 3 things can influence ejection fraction?
Ventricular pre-load
Myocardial contractility
Ventricular afterload
What is ‘pre-load’?
Volume of blood in the ventricles at the beginning of systole
What is the main contributor to pre-load? What theory is this based on?
Venous return
Starling’s law
What is Starling’s law?
The greater the venous return > the greater the filling (pre-load) > greater stretch on the myocardium > stronger ventricular contraction
What factors influence pre-load?
Posture Blood volume Sympathetic tone Intrathoracic pressure Intrapericardial pressure Exercise
What is myocardial contractility?
The force generated by the heart in ejecting blood from the ventricles
What factors influence contractility?
Pre-load Increased ANS activity Hormones (eg. adrenaline) Stress Ischaemia Damaged/diseased myocardium
What is ‘after load’? Dictated by what?
Tension in the myocardium during contraction
What the blood has to be contracted against
Dictated by systemic vascular resistance (SVR)
What factors affect SVR?
Vessel length
Vessel radius
Viscosity of blood
What is laminar flow?
Blood flows faster in centre of vessel and slower at the edges
Blood pressure (BP) =
Cardiac output (CO) x Systemic vascular resistance (SVR)
Why does post-exercise hypotension occur?
Reduced SV and therefore reduced CO > Leads to reduced BP
Following exercise, vessels remain dilated > leads to reduced BP
What is the effect of Nitric Oxide in vessel walls?
Relaxes smooth muscle