Cardiology Flashcards
(190 cards)
stable angina is due to
fixed atherosclerotic lesion
stable angian occurs when
oxygen deman exceeds available blood supply
7 risk factors for stable angina?
- diabetes mellitus (worst risk factor)
- hyperlipidemia (high LDL)
- hypertension (most common risk factor)
- smoking
- age (men > 45, women > 55)
- low level of HDL
- family hx of prematrue coronary artery dz (CAD) or MI in first relatives
5 clinical presentation for CAD?
- asymptomatic
- stable angina pectoris
- unstable angina pectoris
- MI (either NSTEMI or STEMI)
- sudden cardiac death
what is the goal of LDL in all CAD pts?
below 100 mg/dl
2 prognostic factors for CAD
- Lt. ventricular function (ejection fraction): less than 50% –> inc mortality
- vessels involved: Lt main coronary a (poor prognosis b/c it covers approximately 2/3 of the heart)
4 clinical features of stable angina?
- chest pain or substernal pressure sensation
- brought on by factors that inc myocardial oxygen deman such as exertion or emotion
- relieved by rest or nitroglycerin
- pain that does NOT change with breating nor with body position
3 characteristics of pain of stable angina
- last less than 10 to 15 min (usually 1 to 5 min)
- frightening chest discomfort, usually described as heaviness, pressure, squeezing, tightness (rarely described as sharp or stabbing pain)
- pain is often gradual in onset
best initial test for all forms of chest pain?
ECG
3 applications of stress ECG (exercise testing)?
- to confirm diagnosis of angian
- to evaluate response of therapy in pts with documented CAD
- to identify pts with CAD who may have a high risk of actue coronary events
4 symptoms that give the positive result for stress test?
- ST segment depression
- chest pain
- hypotension
- significan arrythmia
define metabolic syndrome X
any combination of hypercholesterolemia, hypertriglyceridemia, impaired glucose tolerance, diabetes, hyperuricemia, HTN
6 ways to dianogse CAD
- physical exams are normal in most pts with CAD
- resting ECG (usually normal)
- stress test (stress ECG, stress echocardiography)
- pharmacological stress test (if pt can’t exercise)
- holter monitoring (ambulatory ECG)
- cardiac catheterization with coronary angiography
what is stress test particularly useful for what pt group?
pts with an intermediate pretest probability of CAD based on age, gender, symptoms.
name 3 types of stress tests
- stress ECG
- stress echocardiography
- info gain from stress tests can be enhanced by myocardial perfusion imaging after IV administration of a radioisotope such as thallium 201 during exercise
what is the sensitivity of stress ECG?
75% if pts are able to exercise sufficiently to increase heart rate to 85% of max predicted value for age.
how do you calculate tat max heart rate using stress ECG?
220 - age
on ECG of a pt who is going through an exercise induced ischemia will show
ST segment depression (subendocardial ischemia)
other than ST segment depression of ECG, what is the + findings from a stress test?
onset of heart failure or ventricular arrhythmia during exercise
what is the next step for pts with a positive stress test?
cardiac catheterization
when do you perform stress echocardiography?
before and immediately after exercise
positive signs from stress echo?
wall motion abnormalities (eg. akinesis or dyskinesis) not present at rest
why is stress echo favored over stress ECG?
more sensitive in detecting ischemia, can assess LV size and function, can diagnose valvular dz, and can be used to identify CAD in the presence of preexisting ECG abnormaltieis
what is the definitive test for CAD?
cardiac catheterization with coronary angiography