Flashcards in Cardiomyopathy Deck (10):
Most familial cardiomyopathies are inherented in an autosomal dominant pattern
Genetic cardiomyopathy is characterized by age dependence and incomplete penetrance
The most commonly recognized genetic causes of dilated cardiomyopathy are structural mutations of ____.
Hallmark of congestion
Defects in the cytoskeletal proteins can lead to cardiomyopathy, usually with a dilated phenotype
Sarcolemmal membrane protein defects are associated with dilated cardiomyopathy.
Defects in the sarcolemmal channel proteins (channelopathies) are generally associated with primary arrhythmias.
Mutation in SCN5A (channelopathy) have been implicated in dilated cardiomyopathy with conduction disease.
Nuclear membrane protein defects are associated with a higher prevalence of artrial arrhythmias and conduction system disease.