Cardiorenal Syndrome Flashcards Preview

N5160 > Cardiorenal Syndrome > Flashcards

Flashcards in Cardiorenal Syndrome Deck (25)
Loading flashcards...
1

______ _______dysfunction and ______dysfunctional frequently coexist in the same individual

left ventricular ; renal

2

The pathophysiological basis for cardiorenal syndrome is that ___________

dysfunction in 1 organ lead to dysfuntion in the other organ

3

Renal disease is associated with low _____ _____ such as _____ where renal blood flow is ________

cardiac output; HF; decreased

4

Medications known to worsen renal function

Diuretics

5

What plays a critical role in HF and is a prominent factor in renal dysfunction?

Neurohormonal Stimulation

6

What are the two systems that preserve the integrity of the arterial circulation and maintenance of blood flow to the vital organs?

Renin-angiotensin-Aldosterone system
Sympathetic nervous system

7

The NH response is initially compensatory but if left untreated lead to ________and _______ kidney injury

progressive; irreversible

8

CRS Type I Acute worsening of the _____ leading to ______Injury/dysfunction.

Acute cardiorenal syndrome. heart function; kidney

9

CRS Type II ________abnormalities of the _____ leading to ______Injury/dysfunction.

Chronic Cardiorenal syndrome; Chronic; heart; kidney

10

CRS Type III : Acute worsening of the _______ leading to _____injury or dysfunction.

Acute Renocardiac syndrome: kidney; heart

11

CRS type IV: Chronic ________ leading to ______ injury or dysfunction

Kidney injury ; heart

12

CRS Type V: Secondary Cardiorenal syndrome defined as ______Conditions leading to simultateneous injury or dysfunction of _____ and ______

systemic;

13

Most common cause of CRS type I

nonadherence to dietary or medication regimens

14

In CRS Type I there is alterations in _____ ______ and _____ ____ _____ as well as _______ ________

Cardiac output: intra-cardiac filing pressures; peripheral vasoconstriction

15

T or F : In ACS or cardiogenic shock , the risk of CRS type I is high despite the use of inotropes, vasopressors.

True

16

What is the focus in CRS type 3?

prevention

17

Medications known to worsen renal function

ACE
Diuretics
ARBs
anti-hyperlipidemics

18

Patients with CKD are more likely to die of _________than to progress to dialysis

CVD

19

2 Stronger predictors for worsening renal function are:

Hypertension and Hypervolemia

20

Cautionary approach to the treatment of patients with CRS type I is to assume that _______ is a direct result of _____ ______ until otherwise identified

AKI; renal hypoperfusion

21

What help tailor appropriate therapy

Hemodynamic and volume status

22

Mainstay of therapy for CRS Type I

Loop diuretics
Vasodilators (nitrates and Nesiritide)

23

Target fluid removal rate of

500ml/hr

24

Concomittant HF and ______ insufficiency cause a shift in the diuretic "dose-response-curve" to address this challenge current guidelines advocate the use of ______doses of Loop diuretics or adding a ____ ______ that acts on a ___ ______ such as _______

higher; second loop diuretics; distal tubule; metolazone.

25

Vasodilators provide hemodynamic benefits by (Increasing or decreasing) both _____ preload and afterload, leading to improvement is ________ , ______ and _______

Decreasing; cardiac output, BP and stroke volume