Cardiovascular and Renal Flashcards

(40 cards)

1
Q

A patient has been prescribed lidocaine (Xylocaine). What does the nurse understand as the reason for this medication order?

A

Ventricular arrhythmias:

Lidocaine is a sodium channel–blocking drug used specifically to treat ventricular arrhythmias.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

The nurse is reviewing emergency protocols and administration of adenosine (Adenocard). What is a vitally important task to remember when administering adenosine?

A

Give it as a rapid intravenous push.
Adenosine must be given as rapidly as possible, followed by a 50-mL normal saline flush in order to get all of the medication into the circulation quickly since the half-life of adenosine is less than 10 seconds.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

To prevent the occurrence of cinchonism in a patient prescribed quinidine, what does the nurse emphasize as important?

A

Avoid drinking grapefruit juice.

Grapefruit juice can also inhibit the metabolism of quinidine, which increases the risk of cinchonism.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Adenosine is used to treat which condition?

A

Paroxysmal supraventricular tachycardia (PSVT):

The only therapeutic indication of use for adenosine is the treatment of PSVT.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Sodium channel blockers are considered which class of antidyshythmic drugs?

A

Class I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

The patient has been prescribed ibutilide (Corvert), a class III antiarrhythmic drug. The nurse is aware that this drug has been prescribed for which reason?

A

Conversion of recent-onset atrial fibrillation and flutter:

Ibutilide is specifically indicated only for treatment of recent-onset atrial fibrillation and flutter.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Before administering a dose of an antidysrhythmic drug to an assigned patient, which assessments would be of highest priority?

A

Apical pulse and blood pressure:
Antiarrhythmic drugs can cause both hypotension and bradycardia; therefore it is important to assess blood pressure and apical pulse before administration. Peripheral pulses are not as reliable as the apical pulse assessment.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which class of drugs is used to treat both hypertension and dysrhythmias?

A

Calcium channel blockers:
Calcium channel blockers are effective in treating both hypertension and dysrhythmias secondary to their negative inotropic and chronotropic effects.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Calcium channel blockers have which pharmacodynamic effect?

A
Coronary vasodilation:
Calcium channel blockers cause 
coronary vasodilation, 
a negative inotropic effect, 
a negative chronotropic effect, and 
a negative dromotropic effect.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

The most severe adverse effects of amiodarone are evidenced in which body system?

A

Pulmonary:
Patients taking amiodarone must have baseline and serial pulmonary function tests in order to monitor for potential pulmonary toxicity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

For which potential adverse effects would the nurse monitor patients prescribed amiodarone? (Select all that apply.)

A

Bluish skin discoloration
Hypothyroidism
Photosensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

any deviation from the normal rhythm of the heart

A

dysrhythmia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

“no rhythm” implies asystole or no heartbeat at al

A

arrhythmia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

when antidysrhythmic drugs cause dysrhythmias

A

prodysrhythmic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SA node

A

the natural pacemaker of the heart because it spontaneously depolarizes the most frequently; have a slower upstroke velocity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

resting membrane potential (RMP)

A

an important determinant of the rate of its impulse conduction to other cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Common Dysrhythmias

A

Supraventricular dysrhythmias;
Ventricular dysrhythmias;
Dysrhythmias

18
Q

Supraventricular dysrhythmias

A

originate above the ventricles in the SA or AV node or atrial myocardium.

19
Q

Ventricular dysrhythmias

A

originate below the AV node in the His-Purkinje system or ventricular myocardium

20
Q

Dysrhythmias

A

originate outside the conduction system (i.e., in atrial or ventricular cells) are called ectopic and their points of origin are called ectopic foci

21
Q

Conduction blocks

A

dysrhythmias that involve disruption of impulse conduction between the atria and ventricles through the AV node, directly affecting ventricular function
may originate in the His-Purkinje system

22
Q

Class I

A

Membrane-stabilizing drugs (e.g., class Ia, quinidine; class Ib, lidocaine; class Ic, flecainide); these drugs exert their actions on the sodium (fast) channels

23
Q

Class II

A

Beta-adrenergic blockers that depress phase 4 depolarization (e.g., atenolol);
commonly used as antihypertensives, working by blocking sympathetic nervous system stimulation to the heart and, as a result, the transmission of impulses in the heart’s conduction system. These drugs mostly affect slower-conducting cardiac tissues

24
Q

Class III

A

Drugs that prolong repolarization in phase 3 (e.g., amiodarone and dofetilide); these drugs affect fast tissue and are most commonly used to manage dysrhythmias that are difficult to treat

25
Class IV
Calcium channel blockers that depress phase 4 depolarization (e.g., verapamil); these drugs work specifically by inhibiting the calcium channels, which reduces the influx of calcium ions during action potentials. Diltiazem and verapamil are the calcium channel blockers most commonly used to treat cardiac dysrhythmias
26
Adverse effects common to most antidysrhythmics
hypersensitivity reactions, nausea, vomiting, and diarrhea. Other common effects include dizziness, headache, and blurred vision
27
toxic effects of the antidysrhythmics
heart, circulation, and central nervous system (CNS)
28
interactions
result in dysrhythmias, hypotension or hypertension, respiratory distress, or excessive therapeutic or toxic drug effects
29
signs and symptoms to assess for decreased cardiac functioning (as a result of dysrhythmia and decrease in cardiac output)
apical-radial pulse deficits, jugular vein distension, edema, prolonged capillary refill (longer than 5 seconds), decreased urinary output, activity intolerance, chest pain or pressure, dyspnea, and fatigue
30
administering antidysrhythmic
Review any baseline ECGs; vital signs with attention to blood pressure, postural blood pressure, heart sounds, and heart rate, rhythm, and quality; Document any changes in level of alertness, increase in anxiety levels, syncope, or dizziness
31
lidocaine
assess the cardiovascular system, with attention to heart rate and blood pressure.
32
Amiodarone
assess respiratory, thyroid, hepatic, dermatologic, and/or hypertensive conditions due to possible drug-related pulmonary toxicity, exacerbation of thyroid disorders, abnormal liver function tests, and rash; gastrointestinal upset, may be prevented or decreased by taking the drug with food or a snack; Photosensitivity and photophobia
33
notify the prescriber
prolongation of the QT interval by more than 50%; pulse rate is lower than 60 beats/min
34
Beta blockers
diltiazem, and verapamil may all be used to manage abnormal rhythms and are to be given only after checking and documenting pulse rates and blood pressures; withhold if pulse rate is 60 beats/min or lower or 100 beats/min or higher and/or the systolic blood pressure is 90 mm Hg or lower.
35
Dofetilide
monitor for any changes in the ECG; report chest pain, nausea, or diarrhea, to the prescriber immediately
36
Adverse effects for the class I antidysrhythmics
procainamide: hypotension, rash, diarrhea, systemic lupus erythematosus, SLE–like syndrome; quinidine: ECG changes, bitter taste, anorexia, blurred vision, and tinnitus; and phenytoin: gingival hyperplasia and decrease in blood pressure and pulse rate
37
Adverse effects for class II beta blockers
may cause bradycardia, AV block, heart failure, bronchospasm, and changes in blood glucose levels
38
Adverse effects for class III
Amiodarone: may lead to pulmonary toxicity, thyroid disorders, decrease in blood pressure and pulse rate, photosensitivity, and abnormal liver function
39
Adverse effects for class IV Calcium channel blockers
are associated with heart block, hypotension, constipation, dizziness, and dyspnea
40
therapeutic responses to antidysrhythmics
decrease in blood pressure in hypertensive patients, a decrease in edema, and restoration of a regular pulse rate