Cardiovascular: HTN/HF- Quizlet Questions

Question 1

Pharmacologic treatment for HTN is indicated for primary prevention

Answer 1

No CVD, 10 year ASCVD <10%, and SBP >=140 or DBP >=90 OR NoCVD, 10 year ASCVD >=10% and SBP >=130 or DBP >=80

Question 2

First line pharmaceutical options for treatment of HTN

Answer 2

Diuretics, ACE inhibitors, ARBs, CCB

Question 3

Class of antihypertensive drug that should be used with caution in individuals with gout

Answer 3

Thiazide diuretics

Question 4

Pharmacologic agent that prevents conversion of Angiotensin 1 to Angiotensin II

Answer 4

ACE inhibitor

Question 5

Antihypertensive of choice (2) in the black population

Answer 5

Thiazide diuretics and CCB

Question 6

Antihypertensive of choice for individuals with CKD

Answer 6

ACE inhibitor (or ARB if not tolerated)

Question 7

Side effect of ACE inhibitors related to blocking of bradykinase

Answer 7

cough

Question 8

Mechanism of Action: ARB

Answer 8

Blocks access of angiotensin II

Question 9

Mechanism of Action: CCB

Answer 9

Blocks calcium influx resulting in vasodilation

Question 10

Block only Beta receptors in heart and kidneys

Answer 10

Cardioselective Beta Blocker

Question 11

Class of antihypertensive that should be used cautiously in individuals with lung disease

Answer 11

Non selective beta blocker

Question 12

Class of antihypertensive that has a common side effect of orthostatic hypotension

Answer 12

Alpha blockers

Question 13

Hypertension caused by a comorbid condition or drug

Answer 13

Secondary Hypertension

Question 14

Cornerstone of treatment of HF

Answer 14

Ace inhibitors and beta blockers

Question 15

Drugs routinely used in addition to ACEI and Beta blockers in HFREF (Stage C)

Answer 15

Diuretics (loop) and Aldosterone antagonist (spironolactone)

Question 16

Goal in dosing ACE inhibitors in HF

Answer 16

Maximal dose tolerated

Question 17

Medication class that minimizes cardiac remodeling

Answer 17

ACE inhibitors

Question 18

Goals of treatment of HF (Stage A)

Answer 18

Healthy lifestyle, prevent vascular/coronary disease, prevent LV structural abnormalities

Question 19

Class of diuretic most commonly used to treat HF

Answer 19

Loop diuretics (e.g. furosemide, bumetanide)

Question 20

Common OTC analgesic that interacts with loop diuretic

Answer 20

NSAIDs

Question 21

Drug recommended for treatment of HF and SVT or atrial fibrillation

Answer 21

Digoxin

Question 22

Effect of combination of isosorbide dinitrate and hydralazine

Answer 22

Decrease preload and afterload

Question 23

Major adverse effect of aldosterone antagonists / Mineralcorticoid receptor antagonists

Answer 23

Hyperkalemia and renal failure

Question 24

Mechanism of action of Mineral corticoid receptor antagonists

Answer 24

Inhibit aldosterone to produce a mild diuretic effect and potassium sparing

Question 25

Medication used to treat HF that may have endocrine side effect profile such as gynecomastia in men and menstrual irregularity in women

Answer 25

Sprinolactone

Question 26

Effect of digoxin

Answer 26

Positive inotrope (increase contractility)