Cardiovascular system Flashcards

1
Q

Which chamber of the heart delivers blood to the systemic circulation?

A

The left chamber

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2
Q

What chamber of the heart transports blood to the lungs?

A

The right chamber

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3
Q

Oxygenated/deoxygenated blood returns to the RHS of the heart

A

Deoxygenated

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4
Q

Name the upper chamber of the heart

A

Atrium

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5
Q

Name the lower chamber of the heart

A

Ventricle

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6
Q

The superior vena cava returns blood from…

A

Head & neck region, arms & chest

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7
Q

The inferior vena cava returns blood from…

A

The organs below the heart, legs & feet

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8
Q

What is the role of the pulmonary artery?

A

It transports deoxygenated blood to the lungs for gas exchange

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9
Q

What is the role of the pulmonary vein?

A

It brings oxygenated blood back to the left atrium of the heart

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10
Q

Describe the pericardium

A

A multilayered sac with an outer fibrous covering with an inner secretory lining

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11
Q

The fibrous portion of the pericardium is composed of…

A

Dense irregular connective tissue

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12
Q

The inner serous/secretory lining of the pericardium is composed of…

A

Thin connective tissue

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13
Q

What is the inner lining of the ventricles called?

A

Trabeculae

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14
Q

Describe the microscopic features of myocardial cells

A

They are multinucleated, branched and elongated cells

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15
Q

What three types of cell junctions exist in intercalated discs?

A

Fascia adherens, desmosomes/macula adherens & gap junctions

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16
Q

What node initiates an action potential to generate electrical impulses and where is it located?

A

The sinoatrial (SA) node
Located in the upper right atrium

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17
Q

What is the function of the atrioventricular (AV) node?

A

It receives the impulse from the SA node and delivers it to the AV bundles/bundles of His

18
Q

What happens when the Purkinje fibres receive electrical impulses?

A

The ventricles contract

19
Q

The endothelium is…

A

The epithelial lining of blood, lymph vessels and the heart

20
Q

Which side of the heart has a bicuspid valve?

21
Q

What happens when the atrioventricular (AV) valves close?

A

Contraction of the ventricles

22
Q

Baroreceptors detect…

23
Q

How is blood pressure maintained by the parasympathetic nervous system?

A

Parasympathetic nervous system reduced heart rate & force of atrial contraction

24
Q

Describe the role of autorhythmic cells in the heart

A

They are responsible for depolarisation to threshold potential without neural input

25
Sistole refers to...
The contraction of the ventricles, leading to ejection of blood
26
Diastole refers to...
Relaxation of the heart - where the ventricles fill with blood
27
List the three main structural differences between veins and arteries
Veins lack elastic laminae, have valves and have a wider lumen
28
What is the role of the metaarteriole?
It diverts blood to the dermis by closing blood supply to the capillary bed
29
How does baroreceptor firing rate change to increase BP?
Baroreceptor firing rate decreases
30
Name the too blood pressure sensors
Carotid sinus and aortic arch
31
What happens when the beta 2 receptor is stimulated?
It decreases blood pressure by decreasing TPR
32
What hormone stimulates beta 1 adrenergic receptors?
Adrenaline
33
What happens when beta 1 receptors are stimulated?
Heart rate increases. Vasoconstriction.
34
What organ is a major blood pressure sensor?
Kidneys
35
Why is there an action potential delay when it reaches the AV node?
Different structure to SA node. Allows ventricles to fill with blood from atria.
36
What is the role of autorhythmic cells?
They depolarise to threshold without neural imput through repeated AP generation
37
What two ion channels open during the pacemaker potential?
Na funny channels and T-type Ca channels
38
The intake of what ion causes the restoration of the membrane potential in autorhythmic fibres?
K ions (potassium)
39
Preload refers to...
The stretch of the heart walls at the end of diastole (heart relaxes)
40
Afterload refers to...
Ventricular contraction at the end of systole. Pressure in pulmonary trunk is overcome before blood ejection