Cardiovascular System: Blood Flashcards
(20 cards)
formed elments in the blood
erythrocytes, leukocytes, platelets
erythrocytes
anucleate and no organelles, anaerobic (glycolysis = energy, short life span (3-4 mo), biconcave (large surface area)
sickle cell disease
hemoglobin is off by one amino acid
abnormal hemoglobin can crystalize; causes sickling
-only survive 10-20 days
-cause pain
-often block blood flow
anemia
low oxygen carrying capacity
not enough Fe= hemoglobin not made
not enough Oxygen carried to tissues = fatigue
leukocytes
complete cells (nucleus and organelles)
immune response; increase in number with infection
how are leukocytes able to move through capillary walls?
diapedesis
A blood type antigen
A-antigen
A blood type antibody
Anti-B
B blood type antigen
B-antigen
B blood type antibody
Anti-A
AB blood type antibody
NONE
AB blood type antigen
A-antigen, B-antigen
O blood type antibody
Anti-A, Anti-B
O blood type antigen
NONE
____ is needed in erythropoiesis
Fe
erythropoiesis
production of RBCs from stem cells in red bone marrow
RBC production occurs in
the red bone marrow
Surprisingly, the abnormal cytoskeleton of the “abnormal” RBCs due to sickle cell disease diminish chances of dying from
malaria parasite (pathway used by parasite is disrupted)
When does the Rh factor become a problem?
Rh(-) woman / Rh(+) man > conceive child
Rh (-) woman has Rh(+) fetus
–> cells from Rh positive (+) fetus enter womans Rh(-) blood stream
=woman becomes sensitized to antibodies to fight Rh (+) blood cells
–> in next Rh positive pregnancy, maternal antibodies attack fetal RBCs
Rh factor either present (+) or absent (-) on
erythrocytes
