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(20 cards)
Clin f of carcinoid syndrome
flushing
diarrhea
bronchospasm
hypotension
What drug class/ MOA of rivaroxaban
direct faxtor ten A inhibitor
What is the MC inheritable form of CRC
Lynch syndrome/ HNPC
How to tell drug indiced parkinsonism to parkinson’s disease
motor sx are rapid onset and bilateral
rigidity and rest tremor are uncommon
What blood changes can occur in severe sepsis
neutropenia
Ix for celiac disease
Reintroduce gluten for at least 6 weeks prior to testing:
1. IgA TTG abs
+ endomyseal Ab IgA –> look for selective IgA deficiency which would give a false negative results
2. Gold standard: endoscopic intesitnal bx -> villous atrophy, crypt hyperplasia, increase in intraepithelial lymphocytes
What is the most common inherited bleeding disorder
Von willebrands
Ix findings in von willebrands disease
increased bleeding time, increased APTT, mildly decreased factor 8
IBS mng
- Acc to predom sx
Pain - antispasmodic
Constip - laxatives, not lactulose - linaclotide
Diarrh- loperiamide - low dose TCA preferred over SSRIS
If no response to pharm after 12mo: psychological
Lifestyle: reg meals + take time, avoiding missing meals or leaving long gaps between, drink > 8 cups water/ day, decreased ETOH and fizzy drinks
What infectious organism can trigger an aplastic crisis in pts with hereditary spherocytosis
parvovirus
Features of tension PTX
Tracheal dev
Resonant to percussion
Absent breath sounds
- all in the contect of resp distress and shock
What is an aplastic crisis
Sudden, severe decrease in RBC production
Seen in pts with sickle cell disease, hereditary spherocytosis
Often triggered by inf parvovirus
What blood abnormality does SLE cause
neutropenia
Blood results in refeeding syndrome
decreased phosphate, decreased potassium, decreased magnesium
What do auer rods on blood film suggest
Acute promyelocytic leukemia
Cell type in chronic lymphocytic leukemia
Well diff lymphocytes
What blood abnormality can EBV cause
neutropenia
Which imaging modality is used for staging Hodgkin’s lymphoma
PET/ CT
Length of anticoag for VTE
Provoked = 3 mo
Unprovoked = 6 moo
What cell type are diagnostic of hodgkin’s lymphoma
Reed sternber cells = mirror image nuclei
