Case List- Gyn Flashcards
Ectopics
-incidence
-risk factors
-heterotopic incidence
-with IVF
-2%
-prior ectopic, prior tubal surgery, adhesive disease (endometriosis), PID, ruptured viscous
-1/30K
-1/100
What antibiotics do you use for PID?
Ceftrixone, Doxycycline, Flagyl
CPP
- definition
-differential diagnosis
Pain perceived to originate from pelvic organs > 6 months
Ddx: cervicitis, chronic PID, adenomyosis, hydrsalpinx, ovarian cysts/tumors, endometriosis, adhesion, urological- PBS, urethral diverticulum, IBS, diverticulosis, celiac disease, deprressoin/anxiety, PTSD, myofascial
Chorionic villi on histology
small like finger projections
MTX ABSOLUTE CIN
-IUP/heterotopic
-breastfeeding
-leukopenia/thrombocytopenia
-RUPTURED ECTOPIC
-HD unstable
-inability to follow up
-severe hepatic.renal disease
-active PUD
-active pulmonary disease
MTX relative CIN
-refusal to accept blood
-GS > 4 cm
-HCG high initially (5000) - higher failure rate
-Live ectopic
5 Case
-risks of ectopic general population
-risks of ectopic with IUD LNG
-risks of perforationion
-high risk for ectopic with IUD LNG or Cu?
1) 2%
2) <1% (0.09)
3) 1/1000
4) higher risk of an ectopic with Copper IUD
How do you dose MTX?
-say SINGLE DOSGING IM
HCG DAY 1 AND DAY 4 AND 7
Decline of 15% between 4-7
If no decline and patient continues to be stable, consider repeat MTX vs. surgical therapy.
-if declining, follow HCG weekly until negative
-If receive two doses and inadequate response, proceed to surgery!
What is the baseline risk for miscarriage?
What percent occur during 1T?
How does anesthesia affect miscarriage risk?
Baseline risk of fetal anomaly?
10%
80% in first trimester
Some studies show slight increase of miscarriage in first half of pregnancy, uncertain if this is due to anesthesia, bodies response to surgery or illness
5%
Medical management of SAB with
-expectant
-Cytotec
-Mifepristone + cytotect
-80% (up to 8 weeks)
- 80% (single dose is 70%)
-significantly increased success and decreased need to surgical therapy
TXA MOA
Dose: 1.3 mg TID PO or 1 gram IV in 100 ml over 10 minutes
prevents plasmin formation, thus stabilizing the fibrin matrix
- What are CIN to anti-fibrinolytic therapy.
Allergy, VTE history, intracranial bleeding, known defective color blindness
What are the chances of each type of hyperplasia progressing to cancer for each type?
o Simple without atypia 1%
o Complex without atypia 3%
o Simple with atypia 9%
o Complex with atypia (EIN) 40%
What is DDX of Post menopausal bleeding?
Endometrial atrophy, polyp, leiomyoma, hyperplasia, EIN, atrophic vaginitis, urological conditions/stones
When do you hault a Hscope?
In a healthy individual, I assess around 1000 however haulting the procedure is necessary at 2500
-Fluid deficit would be 750 to 1000
Risks of endometrial polyp malignancy
- Premenopausal 2%
- Post menopausal 5%
What about CERVICAL POLYPS, risk of malignancy?
close to 2% malignant
higher risk if post menopausal
Do you do routine cystoscopy?
No. I find the ureteral course at the start of my hysterectomies and follow the ureter into the pelvis. When I am coagulating and transecting the uterine vascular pedicle, I stay medial. I do a cystoscopy if there is extensive dissection along the pelvic side wall outside of the norm.
I also work in a group where we do a high volume of laparoscopic hysterectomies. With a laparoscopic hysterectomy the highest likelihood of an injury is through thermal injury at the time of coagulating the cardinal ligaments, a cystoscopy will not detect a delayed thermal injury.
How do you determine route of hyst?
Though I know a vaginal hysterectomy is the preferred route of hysterectomy, I first and foremost determine if the patient is a good candidate for a VH.
-gravidity
-surgeries
-risks for adhesions
-vaginal caliber
-descensus
- uterine size/symmetry
If there is limited descensus or an extensive surgical history to include multiple abdominal surgeries with risks of adhesive disease, then I consider the next minimally invasive option, a laparoscopic hysterectomy. The decision between robotic vs. laparoscopic is made based on the uterine size, body habitus, patient comorbidities, OR availability, and through shared decision making, as well as the potential for extensive adhesive disease.
In my current clinical practice, I am a referral basis for the robot. I consider the above criteria and if the patient is a candidate for a minimally invasive approach, I discuss these approaches. I am most comfortable with robotic hysterectomies and have well trained support staff.
If the patient is not a candidate due to uterine size or concerns for significant anterior abdominal wall adhesions, then we talk about TAH vs. referral to a gyn onc.
l also assist my partners with their TLH’s and VH. In the next 5 years, I would like to become more proficient with VH, and I am in the process of doing so with my senior partners as my mentors. I would like to incorporate more VH’s into my practice if there is a good candiate.
Hysterctomy and ovary removal
speal
-risks of subsequent ovarian surgery if ovaries left inset?
Risks ovarian cancer?
-age
-5% risk of resurgery
1/70 risk ovarian cancer
What is the most common diagnosis of CCP?
What should you do in work up to make sure you aren’t missing anything?
1) endometriosis
2) adhesions
3)IBS
4) PBS/IC
Screen for Anxiety/Dep
What is vulvodynia?
chronic vulvar pain (>3 mo) without an identifiable cause (diagnosis of exclusion)
What is vestibulodynia AKA …
localized vulvodynia
How do you evaluate vulvodynia?
History
Skin complaints
PMH: relevante info- IBS, fibromyalgia, trauma, infection
Hygenic practices
Any allergies
Previous treatments tried
PE: skin eval
neuro eval (anal wink and bulbcavernosus reflex)
Q tip test to locate pain
Rule out vaginitis
Consider biopsy if refractory
MSK: rule out pelvic muscle overactivity/hypertonicity