Cell 3 Flashcards

1
Q

What is the role of the cytoskeleton? long answer

A

Gives the cell shape and mechanical resistance to deformation
Able to contract - deforming the cell and allowing cells to migrate/move
Involved in signalling pathways
Involved in the uptake of extracellular material (endocytosis)
Segregates chromosomes during cellular division
Involved in intracellular transport
Forms specialised structures, such as flagella and cilia

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2
Q

What are the three types of filament within the cytoskeleton?

A

Microfilaments
Microtubules
Intermediate filaments

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3
Q

What is the role of the actin filaments( microfilaments)?

A

Determines the shape of the cell’s surface & control locomotion

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4
Q

What is the role of the microtubules?

A

Determines the positions of membrane - enclosed organelles & direct intracellular transport

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5
Q

What is the role of the intermediate filaments?

A

Provide mechanical strength and prevent stretching
Form a network around the nucleus and extend into the cell periphery
Transmit shearing forces through desmosones between cells.

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6
Q

What provides the epithelial cells attachment to the basal lamina?

A

Hemidesmosones

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7
Q

What are microtubules?

A

Mircrotubules are hollow tubes formed from molecules of tubulin

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8
Q

What are the three cell surface specialisations?

A

Cillia
Flagella
Microvilli

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9
Q

Describe the structure of cillia

A

Hair like cellular appendages with microtubules at the centre
(9+2 arrangement)
Anchored into a basal body

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10
Q

Where is cillia formed?

A

respiratory tract and the female reproductive tract

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11
Q

What is the function of the cillium?

A

to move fluid over the surface of the cell in one direction

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12
Q

Describe the structure of flagella

A

Hair like structure with a bundle of microtubules in the centre

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13
Q

What is the function of flagella?

A

Locomotion

forms a whip-like action /propellor

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14
Q

What motor protein is present in flagella?

A

Dynein

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15
Q

What human cells use a flagellum?

A

Sperm cells (only cell to do so )

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16
Q

Describe the structure of microvillus?

A

Finger like protrusions on the apical surface of epithelium

17
Q

Where are the microvillius generally found?

A

Abundant in the small inestine

18
Q

How is microvilli formed?

A

Formed from actin filaments

19
Q

What is the role of the microvilli?

A

Actin anchors to the terminal web which stiffens the microvilli keeping the actin bundles at right angles to the cell

20
Q

What is the terminal web composed of?

A

Intermediate filaments\

21
Q

What is the role of the cytoskeleton? short answer

A

defines the shape structure and internal organisation of cells

22
Q

Where do microtubules originate?

A

centrosome