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MCAT > Cell Biology 2 > Flashcards

Cell Biology 2 Flashcards

1
Q

SNARE, SNAP and VAMP are associated with which of the following processess?

A

Vesicle and target membrane docking

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2
Q

Which of the following groups of CAMs functions through carbohydrate binding?

A

Selectins

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3
Q

Which of the following is NOT one of the three properties of stem cells?

A

Postmitiotic

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4
Q

During which parts of the cell cycle do chromosomes consist of two chromatids each?

A

Late G2

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5
Q

Which of the following promotes the formation of stable complexes between exportins and their cargo proteins?

A

Ran-GTP

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6
Q

Linker DNA is associated with which histone?

A

H1

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7
Q

In the cytoplasm, as part of the process for moving materials across the nuclear membrane, which of the following converts Ran-GTP to Ran-GDP?

A

Ran-GAP

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8
Q

Which of the following motor molecules consists of one head domain binding domain binding to actin and one tail domain binding to the cell membrane of a cargo vesicle?

A

Myosin I

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9
Q

Which of the following statements is TRUE?

A

Coatamers are removed shortly before docking with their target membranes

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10
Q

Which of the following is located within the membrane phospholipid bilayer and moderates membrane fluidity by restricting movement of phospholipid fatty acid side chains at high temperatures?

A

Cholesterol

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11
Q

Which of the following DOES NOT inhibit microtubular polymerization?

A

Taxol

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12
Q

The structure of biologic membranes can BEST be described as:

A

A fluid-mosaic of proteins interspersed in a phospholipid bilayer

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13
Q

Freeze-fracture of membranes has provided information on the intramembranous distribution of:

A

Proteins

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14
Q

Which of the following statements correctly describes the nucleolus?

A

It is the site for synthesis of rRNA

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15
Q

Nuclear lamins are intermediate filaments that:

A

Line the inner aspect of the nuclear envelope

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16
Q

A connexon is a structural component of the:

A

Gap junction

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17
Q

T/F Each A-microtubule consists of thirteen protofilaments

A

True

18
Q

Which of the following junctional complexes provides a tight seal between adjacent epithelial cells and serves as a barrier for paracellular transport:

A

Zonula occludens

19
Q

During the cell cycle, there are several check points that serve to ensure that everything is ready prior to proceeding to the next stage of the cell cycle. One of these check points is the microtubule assembly check point; this specific check point occurs during which of the following stages of the cell cycle?

A

M

20
Q

Which of the following categories of membrane proteins is represented by proteins that have a hydrophobic domain and two hydrophilic domains?

A

Transmembrane proteins

21
Q

At which stage of mitosis do sister chromatids move to opposite different poles?

A

Anaphase

22
Q

Which of the following phospholipids is found ONLY in the inner leaflet of the plasma membrane?

A

Phosphatidyinositol

23
Q

Which of the following type of epithelium is found in the striated ducts of compound glands?

A

Cuboidal transitioning to columnar

24
Q

Which of the following organelles is characterized by the presence of catalase?

A

Peroxisome

25
Q

Simple vs. compound glands are BEST characterized by which of the following characteristics?

A

Absence vs presence of ductal branching

26
Q

Glands characterized by sebaceous in which the entire secretory cell is lost as part of the secretion are classified as:

A

Holocrine

27
Q

Which of the following organelles is/are characterized by a hydrogen pump?

A

Secondary lysosomes

28
Q

Which of the following components would not normally be found in the mitochondrial matrix?

A

Cytochromes

29
Q

Secondary lysosomes may be associated with:

A

All the above

phagosomes, late endosomes, autophagosomes

30
Q

The G protein consists of several subunits. Which of the following subunits exchanges its GDP for GTP when activated?

A

Alpha subunit

31
Q

Which of the following signal molecules does not bind to an intracellular receptor?

A

Acetylcholine

32
Q

Caspases are generally divided into two groups: initiators and executioners. Which of the following apoptotic pathways utilizes caspase-8 as an initiator caspase

A

Fas pathway

33
Q

Which of the following events is NOT characteristic of apoptosis?

A

Activation of inflammatory processes

34
Q

The transport of proteins into the mitochondrial matrix is assisted by which of the following:

A

Hsp 60 and Hsp 70

35
Q

Which of the following helps to create impermeability to small molecules across the membranes of the mitochondrial cristae?

A

Cardiolipin

36
Q

In the ERK-MAP kinase pathway, activation of the GTP-binding protein Ras interacts with Raf kinase. Raf phoshorylates and activates which of the following?

A

MEK

37
Q

In the JAK-STAT pathway, a ligand binds to a membrane receptor. Associated with this receptor is molecule “A”. Molecule “B” binds to molecule “A”, resulting in the phosphorylation and dimerization of molecule “B”. What is the identification of molecule “B”?

A

STAT

38
Q

This molecule attaches itself to a target protein and marks it for degradation by the 26S proteasome

A

Ubiquitin

39
Q

In the cyclic AMP second messenger pathway which of the following degrades the cAMP?

A

Phosphodiesterase

40
Q

Ends of chromosomes which shorten with each cell cycle and are thought to limit the number of cell divisions are referred to as?

A

Telomeres

41
Q

Coatamers cover which of the following kinds of vesicles?

A

Vesicles being transported from the RER to the cis-Golgi face

42
Q

Transitional epithelium is associated with which of the following systems?

A

Urinary

MCAT (6 decks)

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