Flashcards in Cell Biology - Epithelium Deck (65)
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Command center of the cell
Nucleus
1
The outer nuclear membrane is continuous with what structure in the cell
Endoplasmic reticulum
2
Most abundant form of chromatin
Euchromatin
3
Site of DNA transcription
Nucleus
4
Responsible for ribosomal RNA synthesis
Nucleolus
5
Transcriptionally inactive form of chromatin
Heterochromatin
6
Complex of DNA, histone and non-histone protein
Chromatin
7
Refers to Barr bodies
Heterochromatin
8
Double membrane, continuous with the ER
Nuclear envelope
9
Allows passage of nucleus to the cytoplasm
Nuclear pore
10
Three zones of Nucleolus
Pars granulosa - maturing ribosomes
Pars fibrosa - active zone
Fibrillar center - inactive DNA
11
Site of DNA replication and transcription of DNA into precursors of RNA molecules
Nucleus
12
Double stranded helical molecule that carries the genetic information of the cell
DNA
13
Positively charged proteins important in forming the nucleosome and solenoid fibers in chromatin
Histone proteins
14
Basic repeating unit of chromatin fiber
Nucleosome
15
Barr bodies in Klinefelter syndrome
One - 47 XXY
16
Cell structure that contains their own set of DNA
Mitochondria
17
Site of post-transitional modification
Golgi apparatus
18
Site of sequestration and release of Calcium ions in striated muscles
Smooth endoplasmic reticulum
19
Consists if large and small subunits
Free ribosomes
20
Site for synthesis of steroid hormones, phopholipids and TAG
Smooth Er
21
Protein sorting and packaging site
Golgi apparatus
22
Site of synthesis of secretory proteins, membrane bound proteins and lysosomal enzymes
Rough ER
23
Involved in production of CoA, TCA, beta oxidation and oxidative phosphorylation
Mitochondria
24
Site of ATP synthesis
Mitochondria
25
Site of drug detoxification and fatty acid elongation
Smooth ER
26
Stacks of membranous cisternae with CIS and TRANS face
Golgi apparatus
27
Non-membrane bound vesicle, site of mRNA translation into amino sequence.
Free Ribosome
28
Site of cytosolic and organellar protein
Free Ribosomes
29
Disease associated with mitochondrial genome defect - muscle weakness and pain, seizures, hemiparesis and dementia
MELAS - mitochondrial encephalopathy lactic acidosis and stroke like episodes
30
Cell structure abundant in ovaries, testes and adrenals
Smooth ER
31
Cell structure abundant in neurons, pancreas and thyroid
Rough ER
32
Cell structure abundant in red muscle fiber
Mitochondria
33
Cell's garbage disposal system
Lysosome
34
Contains oxidative enzyme and synthesis of hydrogen peroxide
Peroxisomes
35
Contains hydrolytic enzymes
Lysosome
36
Involved in beta oxidation of long chain fatty acid
Peroxisome
37
Suicide bags of the cell
Lysosomes
38
Participate in bile acid synthesis
Peroxisomes
39
Acid hydrolase is the major protein
Lysosomes
40
Enzymes are produced in free ribosomes
Peroxisomes
41
Enzymes are produced in the RER
Lysosomes
42
Tumor markers, link between the extracellular matrix, cytoplasm and nucleus
Intermediate filament
43
Structure composed of actin
Microfilaments
44
Consists of circularly arranged A and B tubulin proteins
Microtubule
45
Thinnest of all cytoskeleton
Microfilaments
46
Involved in spindle formation during mitosis and meiosis
Microtubules
47
Ciliary and flagellar movement
Microtubules
48
Involve in muscle contraction
Microfilaments - actin and myosin
49
Function inhibited by Amanita mushroom toxin
Microfilaments
50
Associated with Chediak-Higashi syndrome
Microtubules
51
Tumor marker: epithelial cells - squamous carcinoma and adenocarcinoma
Cytokeratin
52
Tumor marker: endothelial cells,vascular smooth muscle, fibroblast and chondroblast
Vimentin
53
Tumor marker: skeletal and smooth muscle
Desmin
54
Tumor marker: neurons
Neurofilament
55
Tumor marker: glial cells
Glial Fibrillar Acidic Protein
56
Tumor marker: inner membrane of nuclear envelope
Laminins A,B, C
57
MAP: ATPase activity for movement of vesicles toward axon terminal - anterograde transport
Kinesin
58
MAP: ATPase activity toward the minus end - retrograde transport
Dynein
59
MAP: ATPase activity for elongation of nerve axons
Dynamin
60
Drug that acts in the microtubules of fungal cells
Griseofulvin
61
Anti-inflammatory drug acts on microtubules of cells
Colchicine
62
Anti-cancer drugs that acts on the microtubules of cancer cells
Vinblastine
Vincristine
Taxanes
63
Keratinized squamous epithelium is only present in the?
Skin, Tongue and Lips
64
