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Flashcards in Cell Biology - Epithelium Deck (65)
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Command center of the cell

Nucleus

1

The outer nuclear membrane is continuous with what structure in the cell

Endoplasmic reticulum

2

Most abundant form of chromatin

Euchromatin

3

Site of DNA transcription

Nucleus

4

Responsible for ribosomal RNA synthesis

Nucleolus

5

Transcriptionally inactive form of chromatin

Heterochromatin

6

Complex of DNA, histone and non-histone protein

Chromatin

7

Refers to Barr bodies

Heterochromatin

8

Double membrane, continuous with the ER

Nuclear envelope

9

Allows passage of nucleus to the cytoplasm

Nuclear pore

10

Three zones of Nucleolus

Pars granulosa - maturing ribosomes
Pars fibrosa - active zone
Fibrillar center - inactive DNA

11

Site of DNA replication and transcription of DNA into precursors of RNA molecules

Nucleus

12

Double stranded helical molecule that carries the genetic information of the cell

DNA

13

Positively charged proteins important in forming the nucleosome and solenoid fibers in chromatin

Histone proteins

14

Basic repeating unit of chromatin fiber

Nucleosome

15

Barr bodies in Klinefelter syndrome

One - 47 XXY

16

Cell structure that contains their own set of DNA

Mitochondria

17

Site of post-transitional modification

Golgi apparatus

18

Site of sequestration and release of Calcium ions in striated muscles

Smooth endoplasmic reticulum

19

Consists if large and small subunits

Free ribosomes

20

Site for synthesis of steroid hormones, phopholipids and TAG

Smooth Er

21

Protein sorting and packaging site

Golgi apparatus

22

Site of synthesis of secretory proteins, membrane bound proteins and lysosomal enzymes

Rough ER

23

Involved in production of CoA, TCA, beta oxidation and oxidative phosphorylation

Mitochondria

24

Site of ATP synthesis

Mitochondria

25

Site of drug detoxification and fatty acid elongation

Smooth ER

26

Stacks of membranous cisternae with CIS and TRANS face

Golgi apparatus

27

Non-membrane bound vesicle, site of mRNA translation into amino sequence.

Free Ribosome

28

Site of cytosolic and organellar protein

Free Ribosomes

29

Disease associated with mitochondrial genome defect - muscle weakness and pain, seizures, hemiparesis and dementia

MELAS - mitochondrial encephalopathy lactic acidosis and stroke like episodes

30

Cell structure abundant in ovaries, testes and adrenals

Smooth ER

31

Cell structure abundant in neurons, pancreas and thyroid

Rough ER

32

Cell structure abundant in red muscle fiber

Mitochondria

33

Cell's garbage disposal system

Lysosome

34

Contains oxidative enzyme and synthesis of hydrogen peroxide

Peroxisomes

35

Contains hydrolytic enzymes

Lysosome

36

Involved in beta oxidation of long chain fatty acid

Peroxisome

37

Suicide bags of the cell

Lysosomes

38

Participate in bile acid synthesis

Peroxisomes

39

Acid hydrolase is the major protein

Lysosomes

40

Enzymes are produced in free ribosomes

Peroxisomes

41

Enzymes are produced in the RER

Lysosomes

42

Tumor markers, link between the extracellular matrix, cytoplasm and nucleus

Intermediate filament

43

Structure composed of actin

Microfilaments

44

Consists of circularly arranged A and B tubulin proteins

Microtubule

45

Thinnest of all cytoskeleton

Microfilaments

46

Involved in spindle formation during mitosis and meiosis

Microtubules

47

Ciliary and flagellar movement

Microtubules

48

Involve in muscle contraction

Microfilaments - actin and myosin

49

Function inhibited by Amanita mushroom toxin

Microfilaments

50

Associated with Chediak-Higashi syndrome

Microtubules

51

Tumor marker: epithelial cells - squamous carcinoma and adenocarcinoma

Cytokeratin

52

Tumor marker: endothelial cells,vascular smooth muscle, fibroblast and chondroblast

Vimentin

53

Tumor marker: skeletal and smooth muscle

Desmin

54

Tumor marker: neurons

Neurofilament

55

Tumor marker: glial cells

Glial Fibrillar Acidic Protein

56

Tumor marker: inner membrane of nuclear envelope

Laminins A,B, C

57

MAP: ATPase activity for movement of vesicles toward axon terminal - anterograde transport

Kinesin

58

MAP: ATPase activity toward the minus end - retrograde transport

Dynein

59

MAP: ATPase activity for elongation of nerve axons

Dynamin

60

Drug that acts in the microtubules of fungal cells

Griseofulvin

61

Anti-inflammatory drug acts on microtubules of cells

Colchicine

62

Anti-cancer drugs that acts on the microtubules of cancer cells

Vinblastine
Vincristine
Taxanes

63

Keratinized squamous epithelium is only present in the?

Skin, Tongue and Lips

64

Eptihelium: sweat glands, developing ovarian follicles

Stratified cuboidal