Cell Development

Question 1

Myeloproliferative

Answer 1

Rapid spread/increase of the bone marrow (myeloid) cells that give rise to red blood cells, granulocytes, monocytes and platelets

Question 2

Lymphoproliferative

Answer 2

Rapid spread/increase of the lymphoid cells, occurs mostly in immunocompromised patients.

Question 3

Acute disease

Answer 3

Rapid onset, short lived, severe, self limiting

Question 4

Chronic disease

Answer 4

Insidious onset, long lasting, recurring

Question 5

Chronic leukaemia

Answer 5

Mostly mature cells, few blast cells seen

Question 6

Acute leukaemia

Answer 6

> 20% blast cells seen

Question 7

Granulocytes

Answer 7

Basophils, eosinophils, neutrophils

Question 8

Immature neutrophils

Answer 8

Myeloblasts, promyelocytes, myelocytes, metamyelocytes, band forms

Question 9

Extramedullary erythropoeisis

Answer 9

Haemopoeisis is occurring outside the bone marrow, in the spleen or liver. Teardrop cells seen in peripheral blood.

Question 10

Extramedullary erythropoesis

Answer 10

Haemopoeisis that occurs outside the bone marrow, in the liver or spleen. Teardrop cells seen in peripheral blood

Question 11

Platelet functions

Answer 11

Haemostasis, coagulation, clot retraction, phagocytosis, storage and transport of histamine and serotonin

Question 12

Thrombocytopenia

Answer 12

Platelets below the NRR. Bone marrow depression, hypersplenism, viral infections.

Question 13

Thrombocytosis

Answer 13

Platelets above the NRR. Idiopathic: splenectomy, epinephrine administration