Cell division Flashcards

(30 cards)

1
Q

When are daughter cells not identical to the parent cell in mitosis?

A

In the rare event of mutation

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2
Q

What period precedes mitosis?

A

Interphase

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3
Q

What happens during interphase?

A

The cell carries out normal functions and the DNA is unravelled and replicated, the organelles grow

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4
Q

What’s the function of the centromere?

A

Joins together the two copies of DNA after replication

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5
Q

What are the stages of mitosis?

A

Prophase, metaphase, anaphase and telophase/cytokinesis

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6
Q

What happens to the chromosomes during prophase?

A

Become visible, initially as long thin threads, they are drawn to the equator of the cell by the spindle fibres attached to the centromere

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7
Q

What are centrioles?

A

Two cylindrical organelles in animal cells, that move to the poles of the cell

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8
Q

What do the centrioles do during prophase?

A

Spindle fibres develop and span the cell from poles, collectively this is called the spindle apparatus

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9
Q

What happens to the nucleus during prophase?

A

Nucleolus disappears and nuclear envelope break down, leaving the chromosomes free in the cytoplasm

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10
Q

When are chromosomes made to be seen as two chromatids?

A

Metaphase

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11
Q

What happens during metaphase?

A

The chromosomes are pulled across the spindle apparatus towards the equator of the cell

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12
Q

What happens during anaphase?

A

Centromeres divide into two and the spindle fibres pull the individual chromatids to poles where they are now considered chromosomes

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13
Q

Where is the energy for anaphase provided from?

A

Mitochondria

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14
Q

What happens if cells are treated with chemicals that destroy the spindle fibres?

A

The chromosomes remain at the equator, unable to reach the poles

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15
Q

What happens to the chromosomes during telophase?

A

The chromosomes reach their respective poles and become longer and thinner, finally disappearing altogether, leaving widely spread chromatin

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16
Q

What happens to the spindle fibres and nucleus during telophase?

A

Spindle fibres disintegrate and nucleolus and nuclear envelope reform

17
Q

What is cytokinesis?

A

The division of the cytoplasm

18
Q

How do prokaryotic cells divide?

A

Binary fission

19
Q

What happens to DNA during binary fission?

A

Circular DNA molecule replicates and both copies attach to the cell membrane, plasmids also replicate

20
Q

What happens to the cell membrane of binary fission?

A

Cell membrane begins to grow and pinch inwards, dividing into two

21
Q

What are the daughter cells of binary fission?

A

Identical circular DNA with variable number of copies of the plasmids

22
Q

How do viruses replicate?

A

Attaching to the host cell with attachment proteins on the surface and injecting nucleic acid with info to replicate it

23
Q

What do host cells produce to replicate the virus?

A

Viral components, nucleic acids, enzymes and structural proteins

24
Q

What are the three stages of the cell cycle?

A

Interphase, nuclear division and cytokinesis

25
What stage occupies most of the cell cycle?
Interphase- 90%
26
What is the typical cell cycle length in a mammalian cell?
24 hours
27
How many cancer diseases are there?
Around 200
28
What causes cancer?
Damage to the genes that regulate mitosis and the cell cycle, leading to exponential growth of abnormal cells causing expanding tumours
29
Where are tumours most commonly found?
Lungs, prostate gland, breast and ovaries, large intestine, stomach, oesophagus and pancreas
30
How does chemotherapy usually disrupt the cell cycle?
Preventing DNA replication, interfering with spindle formation