Cell Division Flashcards
(47 cards)
Cell cycle
G1
S
G2
Mitosis
Cytokinesis
{G1, S, G2 are interphase}
Gap 1
- protein synthesis and replication of organelles
S phase
- DNA synthesis — DNA is replicated
- 2 sister chromatids are held together by centromere
Gap 2
- copied DNA is checked by proof reading enzymes
- if genes aren’t copied correctly, mutations will occur — new cells won’t work
- organelle replication
What is chromatin made up of
DNA + histones
Mitosis
The process or nuclear division where 2 genetically identical nucleus are formed from one parent cell nucleus
Why is mitosis important
- asexual reproduction
- single celled organisms divide to produce 2 daughter cells that are separate organisms
- some multicellular organisms produce offspring from parts of the parent
Do bacteria carry out mitosis?
NO
- they have no linear chromosomes, spindles or centrioles
Prophase
- chromosomes supercoil to shorten and thicken in prophase (condense)
- the nuclear envelope breaks down
- centriole divides in 2 and each daughter centriole goes to pole of cell
- spindle fibres begin to form
Metaphase
- chromosomes line up along equator of the cell
- spindle fibres attach to the centromeres of the chromosome
Anaphase
- the centromere breaks - this separates the sister chromatids
- spindle fibres shorten and pull the chromosomes apart the the poles of the cell
- Each chromatid is identical to the original chromosome in the parent cell it was copied from
Telophase
- new nuclear envelope forms around 2 sets of chromosomes
- spindle fibres break down
- supercoiled chromosomes uncoil into chromatin
Cytokinesis
Mitosis is finished
- cytokinesis occurs and the cytoplasm cleaves to finally produce 2 new genetically identical daughter cells (both identical to parent cell)
- this means daughter cell can do same things the parent cell could do
Differences between animal and plant cell cycles
Animal cells
- most cells will undergo mitosis and cytokinesis
- cytokinesis starts from outside and goes in
Plant cell
- only special cells called meristem cells can divide
- plant cells do not have centrioles
- cytokinesis starts with the formation of a cell plate where the equator was- the new plasma membrane and new cell wall material is then laid down along the cell plate
Cytokinesis in animals, plants & fungi
animals- nip in along ‘cleavage furrow’
plants- along cell plate
yeast (fungi)- budding. Cell undergoes mitosis, then the cell bulges in one side, the new nucleus moves into bulge and the bulge pinched off into a new cell
Meiosis
- 4 daughter cells (haploid)
- genetically different
- start from diploid cells (ovaries & testes)
- gametes
- 2 divisions
Homologous chromosomes
Although they have the same gene, they may contain different alleles from the genes
- because one chromosome is from mum and one from dad
Prophase 1
- chromatin condenses and each chromosome supercoils
- nuclear envelope breaks down and spindle fibres form
- chromosomes arranged in homologous pairs (each have 2 chromatids)
- crossing over occurs where non sister chromatids wrap around each other and may swap sections so that alleles are shuffled
Metaphase 1
- pair of homologous chromosomes still in cross over state attach along the equator of the spindles
- each attach to the spindle by centromere
- pairs are randomly arranged- independent assortment
- the way they line up here determines how they will separate independently in anaphase
Anaphase 1
- chromosomes pulled apart by spindle fibres
- centromeres do not divide, each chromosome consists of 2 chromatids
- crossed over areas separate from each other, resulting in swapped areas of chromosomes and allele shuffling
Telophase 1
- 2 new nuclear envelopes form around each set of chromosomes, cell divides by cytokinesis
- short interphase where chromosomes uncoil
- each new nucleus contains half the original no. of chromosomes, but each chromosome consists of 2 chromatids
in most plant cells, the cell goes straight from anaphase 1 to prophase 2
Prophase 2
- nuclear envelope breaks down
- chromosomes coil and condense
- chromatids no longer identical due to crossing over in prophase 1
- spindle fibres form
Metaphase 2
- chromosomes attach by their centromere to the equator of the spindle
- chromatids randomly arranged
Anaphase 2
- centromeres divide
- chromatids are pulled apart by spindle fibres towards poles
- chromatids randomly separated