Cell Division Flashcards
(28 cards)
What is mitosis?
Type of cell division that produces 2 genetically identical diploid daughter cells
What is meiosis?
Type of cell division that produces 4 genetically different hjaploid daughter cells.
What is interphase?
Longest stage of cell cycle where DNA replication occurs, production of organelles, protein synthesis and other process
What is the role of mitosis?
Growth, repair and replacement of tissues
What is the role of meiosis?
Formation of gametes so that sexual reproduction can occur.
What are the stages of mitosis?
(P)rophase
(M)etaphase
(A)naphase
(T)elophase
What is cytokinesis?
Constriction of the centre of the parent cell from the outside inwards resulting in 2 new cells
What is cytokinesis in plants?
Where a cell plate forms at the equator of the parent cell and a new cell wall is laid down.
What are sister chromatids?
A pair of identical chromatids formed by DNA replication, joined via a centromere.
Describe what happens during meiosis 1 (prophase)
DNA condenses forming chromosomes and visible chromatids. Centrioles divide, migrating to opposite sides of the cell with spindle fibres developing extending from pole to pole. Paternal and Maternal chromosomes associate as homologous pairs (bivalents) in a process called synapsis, twist around one another, joining at chaismata, breaking and rejoining with equivalent chromatid. Nuclear membrane disintergrates and nucelolus disappears leaving the pairs of chromatids free in cytoplasm.
Describe what happens during meiosis 2 (prophase)
Centrioles seperate and form a spindle at right angles to the previous spindle so that there are two spindles for each nucleus produced at telophase 1. The chromosomes condense and the nuclear membrane disappears.
Describe what happens during meiosis 2 (metaphase)
The chromosomes arrange at the equatoe attached to spindle fibres via their centromeres . The centromeres replicate as they are pulled apart.
Describe what happens during meiosis 2 (anaphase)
Spindle fibres contrcat and the centromere split causing teh chromatids to be pulled apart to opposite poles of the cell.
Describe what happens during meiosis 2 (telophase)
The chromatids lengethen and the spindle fibres disappears . The nuclear membrane reforms and cytokinesis takes place.
Describe what happens during meiosis 1 (metaphase)
Spindle fully formed, homologous pairs arrange of equator and attach to spindle fibres at centromere.
Describe what happens during meiosis 1 (anaphase)
Spindle fibres contract causing the bivalent pairs to seperate and be pulled to opposite poles of cell. Chromosomes remain intact.
Describe what happens during meiosis 1 (telophase)
Spindle fibres disappear, nuclear membrane reforms with nucleolus visible around each group of haploid chromosomes and thus have halve the number of chromosmes. Cytokinesis occurs
What may unrestricted mitosis lead to?
Formation of tumors ( Irregular mass of cells that prevent rhe normal function of organs). Thought to occur due to mutations in the genes controlling cell division
How does meiosis produce genetic variation?
- Crossing over of chiasmata in meiosis 1
- Random assortment of maternal and paternal chromsomes during metphase 1.
All result in new combinations of alleles.
Describe what happens during mitosis (prophase)
DNA condenses forming chromosomes and visible chromatids. Centrioles divide, migrating to opposite sides of the cell with spindle fibres developing extending from pole to pole. Nuclear membrane disintergrates and nucelolus disappears leaving the pairs of chromatids free in cytoplasm.
Describe what happens during mitosis (metaphase)
The chromosomes arrange
themselves at the centre or equator of the spindle. The chromosomes become attached to the spindle fibres at the centromere. Contraction of the spindle fibres draws the individual chromatids apart.
Describe what happens during mitosis (anaphase)
Centromeres divide and the spindle fibres contract causing the chromatids to seperate and form individual chromosomes that are then pulled to either side of the cell with the centromeres leading the way.
Describe what happens during mitosis (telophase)
Chromsomes have reached the poles of the cell and begin to uncoil and lengthen. The spindle breaks down and the nuclear membrane reforms with the nucleolus visible.
What is the formula for mitotic index?
No. of cells in any stage of mitosis/ Total number of cells X 100