Cell division Flashcards

Cell division (46 cards)

1
Q

What is the key part of the cell cycle?

A

Cell division

The life of a cell from formation to division into two daughter cells.

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2
Q

What type of daughter cells are produced by most cell divisions?

A

Genetically identical daughter cells

By passing on a complete copy of genetic material (DNA).

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3
Q

What exception to genetic identity occurs during cell division?

A

Meiosis

Generates non-identical daughter cells with half the parent’s DNA.

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4
Q

What is a cell’s genetic material called?

A

Genome

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5
Q

How does the prokaryotic genome typically appear?

A

Single circular DNA molecule

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6
Q

What does the eukaryotic genome consist of?

A

Multiple linear DNA molecules (chromosomes)

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7
Q

How much DNA is contained in a human cell?

A

~2 meters

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8
Q

What are chromosomes made of?

A

Chromatin (DNA + proteins)

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9
Q

What do histone proteins do?

A

Help organize and regulate gene activity

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10
Q

How many chromosomes do human somatic cells contain?

A

46 chromosomes (23 pairs)

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11
Q

How many chromosomes do human gametes contain?

A

23 chromosomes (haploid)

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12
Q

What happens to DNA before cell division?

A

DNA replicates

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13
Q

What are sister chromatids?

A

Identical copies of a duplicated chromosome

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14
Q

Where are sister chromatids held together?

A

Centromere

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15
Q

What does mitosis produce?

A

Two identical daughter cells

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16
Q

What follows mitosis in cell division?

A

Cytokinesis

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17
Q

What is the purpose of meiosis?

A

Produces gametes with half the chromosome number

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18
Q

What is the duration of the human cell cycle?

A

~24 hours

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19
Q

How long does the M phase take?

20
Q

What occurs during the G1 phase?

A

Cell grows, synthesizes proteins and organelles

21
Q

What happens during the S phase?

A

DNA replication occurs

22
Q

What is the main function of the G2 phase?

A

Cell prepares for mitosis

23
Q

What are the five stages of mitosis?

A

Prophase, Prometaphase, Metaphase, Anaphase, Telophase

24
Q

What happens during prophase?

A

Chromosomes condense and mitotic spindle begins to form

25
What occurs during prometaphase?
Nuclear envelope fragments and spindle microtubules attach to kinetochores
26
What is the metaphase characterized by?
Chromosomes align along the metaphase plate
27
What occurs during anaphase?
Sister chromatids separate and are pulled toward opposite poles
28
What happens during telophase?
Two daughter nuclei form and chromosomes decondense
29
How do animal cells undergo cytokinesis?
Cleavage furrow forms and contractile ring pinches the cell
30
How do plant cells undergo cytokinesis?
Cell plate forms from Golgi vesicles
31
What is the role of the mitotic spindle?
Essential for chromosome movement and separation
32
What are centrosomes?
Organize microtubules
33
What are the two mechanisms of chromosome movement?
Pac-Man mechanism and Reeling-in mechanism
34
What is the G1 checkpoint also known as?
Restriction Point
35
What happens if a cell does not receive a go-ahead signal at the G1 checkpoint?
Enters the G0 phase (non-dividing state)
36
What does the G2 checkpoint ensure?
DNA replication is complete and the cell is ready for mitosis
37
What is the role of cyclins in the cell cycle?
Bind to Cdks to activate them
38
What do cyclin-dependent kinases (Cdks) do?
Phosphorylate target proteins to regulate the cell cycle
39
What is MPF?
Maturation-Promoting Factor
40
What are growth factors?
Proteins that stimulate cell division
41
What is density-dependent inhibition?
Crowded cells stop dividing
42
What is anchorage dependence?
Cells must be attached to a surface to divide
43
What characterizes cancer cells in terms of the cell cycle?
Escape normal regulatory signals and divide uncontrollably
44
What is one example of immortalized cancer cells?
HeLa cells
45
What do cancer cells do regarding apoptosis?
Evade programmed cell death
46
What is the conclusion about the cell cycle control system?
Ensures proper division through checkpoints, Cdks, and cyclins