CELL MEMBRANE Flashcards

(43 cards)

1
Q

what the plasma membrane

A

Boundary that separates living cells from its surroundings – makes life possible

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2
Q

amphipathic meaning

A

have both hydrophobic and hydrophilic regions

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3
Q

whats the fluid mosaic

A

fluid structure with a mosaic of protein embedded - phospholipids can move within the membrane

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4
Q

is the lateral motion in the plasma membrane frequent or non frequent

A

frequent

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5
Q

is the flip flop across in the plasma membrane frequent or non frequent

A

non frequent

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6
Q

cholesterol role with the plasma membrane

A

temperature buffer
- has strong enough hydrophobic interactions to anchor itself within the fatty acid tails - preventing it from becoming too fluid at high temp
- has strong enough hydrophilic interactions to interact with the polar head groups - preventing it from becoming too rigid at low temps

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7
Q

3 Types of protein that make up the mosaic

A
  • integral= inserted into hydrophobic middle
  • trans (type of integral protein) = spans the entirety of cell membrane
  • peripheral = on surface
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8
Q

6 Protein functions

A

Transport things across cell surface
Enzymatic activity – break down something / build something up
Signal transduction
Cell–cell recognition
Intercellular joining
Attach to surface

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9
Q

do charged things pass through membrane

A

no

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10
Q

does O2 + CO2 pass through membrane

A

yes - will diffuse freely - nonpolar

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11
Q

what is Selective permeability

A

membrane selects what goes through it

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12
Q

what are transport proteins

A

allow polar / hydrophilic things to go across membrane (can have hydrophilic channel) - specific for what they transport e.g aquaporins transport water

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13
Q

2 types of transport proteins

A

Channel
Carrier

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14
Q

what is passive transport

A

no energy
- uses principles of diffusion (tendency of molecules to spread evenly in space – high -> low conc)

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15
Q

what is active transport and some examples

A

uses energy (ATP) – goes against conc gradient
- Ion pump – sodium potassium pump – electrogenic pump
- Co-transport – sucrose cotransporter
- Bulk transport

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16
Q

whats osmosis

A

diffusion of H2O across a semi permeable membrane

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17
Q

whats hypertonic solution

A

more dissolved in solution outside – H2O moves out (cell = shriveled)
- cell = plazmolyzed in plants

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18
Q

whats hypotonic solution

A

not much dissolved in solution outside – H2O moves in (cell = lysed)
- healthy state for plant cell – cell wall stops it bursting (cell = turgid)

19
Q

whats isotonic solution

A

equal amounts inside and outside of cell - equilibrium
- healthy state for animal cell
- cell = flaccid in plants

20
Q

whats facilitated diffusion

A

transport proteins speed up the passive movement of molecules across plasma membrane e.g. channel and carrier proteins

21
Q

whats Endocytosis and its 3 types

A

brings things into cell
- Phagocytosis (cellular eating - solid)
- Pinocytosis (cellular drinking - liquid)
- Receptor-mediated endocytosis

22
Q

whats Exocytosis

A

takes things out of the cell

23
Q

whats metabolism

A

totality of an organisms chemical reactions
- Metabolic pathways begin with a specific molecule and ends with a specific product

24
Q

whats a catabolic pathway

A

breaks down complex molecules to simpler compounds, releases energy

25
whats an anabolic pathway
builds complex molecules, consumes energy
26
whats bioenergetics
study of how organisms manage energy resources
27
whats energy and its 2 types
capacity to cause change - Kinetic - energy of motion - Potential – energy of position
28
how does ATP work
ATP adds its phosphate to molecules – makes them higher energy, less stable, greater work capacity
29
whats thermodynamics and its 2 types
study of energy transformation - Closed systems – everything is over once reached equilibrium - Open systems – things keep coming into the system (life is open system – energy of sun keeps coming into it)
30
2 laws of thermodynamics
- 1st law = energy of the universe is constant energy can be transferred / transformed but not created - 2nd law = in every energy transfer/transformation, some energy in unusable and lost as heat
31
what is Lost energy called
entropy - disorder
32
Gibbs free (G) energy equation
ΔG = ΔH - TΔS - ΔG - can do work - ΔH - total energy - TΔS - cant do work
33
whats an exergonic reaction
energy released (ΔG < 0) - spontaneous - reaction NOT driven from input of energy (negative ΔG) - REACTANTS have greater capacity to do work + are less stable
34
whats an endergonic reaction
energy required (ΔG > 0) - non-spontaneous - reaction driven from input of energy (positive ΔG - gets given energy) - PRODUCTS have greater capacity to do work + are less stable
35
what does it mean when something has more free energy
- higher G - Less stable - Greater work capacity
36
what does it mean when something has less free energy
- lower G - More stable - Less work capacity
37
what's the activation energy barrier
energy required for reaction to happen – energy speed bump - all reactions have them – spontaneous + non spontaneous
38
how do enzymes lower AEB
Orientating substates correctly Straining substrate bonds Providing a favorable microenvironment Correctly bonding to subsrtate
39
what 2 factors are enzymes affected by
temp + pH
40
what 2 chemicals can influence enzyme activity
- Co-factors – non-protein enzyme helpers – inorganic metals or small organics - Co-enzymes – organic factors
41
2 types of Enzyme inhibitors
- competitive inhibitors – bind to active site of enzyme - Non-competitive inhibitors – bind to a place other than active site – cause confromational change making the active site less efficient (allosterie)
42
what is Allosteric regulation and its 2 types
can inhibit or stimulate enzyme activity – molecule binds to a location and causes a change elsewhere - Activator - stabilizes the enzyme in active form - Inhibitor – stabilizes enzyme in its inactive form
43
what's a Feedback inhibitor
product of a metabolic pathway shuts down the pathway