Cell Membranes Flashcards

1
Q

Name 3 roles of membranes within and at the surface of cells?

A

Act as a partially permeable barrier between the cell and its environment and also between organelles and the cytoplasm within organelles

Site of chemical reactions

Site of cell communication

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2
Q

What is the structure and function of the phospholipid bilayer?

A

Hydrophilic phosphate heads on outside, hydrophobic tails on inside

Central hydrophobic section doesn’t allow water soluble substances to pass through easily = barrier

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3
Q

What is the structure and function of cholesterol?

A

Cholesterol is a lipid with hydrophobic and hydrophilic end

Binds in between phospholipids (to tails) so they’re closer together making the membrane more fluid and stronger

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4
Q

What is the structure and function of glycolipids?

A

Lipid on membrane with carbohydrate chain attached

Stabilise membrane by forming h bonds with surrounding water

Receptors where drugs hormones and antibodies bind

Receptors in cell signalling

Antigens- recognise as self

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5
Q

What is the structure and function of a glycoproteins?

A

And extrinsic protein with carbohydrate chain attached

For cohesion of cells

Receptors for cell signalling

Receptors for drugs hornmones and antibodies

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6
Q

What do proteins do in the cell membrane?

A

Intrinsic proteins - channel and carrier proteins transport molecules across the membrane

Extrinsic proteins - on one side of the bilateral

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7
Q

What is the effect of temperature on membrane permeability?

A

Phospholipids gain kinetic energy = move more

This increases fluidity of membrane and it loses structure
= increase permeability

Channel and carrier proteins denature
- increases permeability

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8
Q

What is the effect of solvents on membrane permeability?

A

Organic solvents can dissolve the lipids in membranes as they are less polar than water
= more permeability

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9
Q

How can you investigate membrane permeability?

A

Using betroot
More pigment released = higher permeability

Higher absorbency on colorimeter

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10
Q

Define diffusion

A

The net movement of particles from an area of high concentration to an area of lower concentration

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11
Q

What is facilitated diffusion?

A

Diffusion across a methane through channel protein (polar substances as inside of Chanel proteins are polar)

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12
Q

Define active transport

A

The movement of molecules from an area of low concentration to high concentration requiring energy ATP
Using carrier proteins

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13
Q
  1. A molecule or ion binds to a _______ in a protein on the cell membrane
  2. Inside the cell _____ binds to the carrier protein and is hydrolysed to __________ and ____
  3. ______ binds to the carrier protein and changes it’s ________
  4. Molecule is _______ into cell
  5. ________ released and recombined with _____ to make _____
  6. Carrier protein returns to original state
A
Receptor
Phosphate 
ADP
Phosphate 
Shape
Released
Phosphate 
ADP 
ATP
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14
Q

Describe endocytosis

A

Phagocytosis (solids) or pinocytosis(liquids)

Membrane invaginates

Membrane enfolds material until it fuses to form a vesicle

Vesicle pinches off and moves to cytoplasm

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15
Q

Describe exocytosis

A

Vesicles formed at the Golgi

Vesicles move to and fuse with cell surface membrane

Contents released outside cell

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16
Q

What happens when an animal cell is placed in a hypotonic solution?

A

It undergoes cytolysis

It bursts

17
Q

What happens when you place and animal cell in a hypertonic solution?

A

In becomes crenated

18
Q

What happens when you place a plant cell in a hypotonic solution

A

It becomes turgid

Doesn’t burst as cell wall is strong and prevents more water entering

19
Q

What happens when you place a plant cell in a hypertonic solution?

A
It becomes plasmolysed
The protoplast ( cell surface menrahe) pulls away from the cell wall
20
Q

How do you investigate diffusion?

A

Using agar jelly as model cells

21
Q

describe the structure of the cell surface membrane

A

phospholipid bilayer containing proteins

hydrophillic heads facing outwards

hydrophobic tails facing inwards

intrinsic-across full width of membrane including carrier and channel rproteins and extrinsic proteins which are on one side of the membrane such as glycoproteins

glycoproteins and glycolipids that are extrinsic and stick out of the membrane

cholesterol between phospholipids

22
Q

what is cell signalling?

A

communication between cells

chemicals released from one cell attaches to and causes change in another cell

23
Q

how are vesicles moved around the cell?

A

by the cytoskeleton

move along the microfilaments which extend or breakdown to move them

uses ATP